This review focuses on new trends in nucleoside biotechnology, which have emerged
during the last decade. Continuously growing interest in the study of this class of compounds …

A survey of the chemo-enzymatic methodology for the preparation of nucleosides of
biological importance is presented. The emphasis is made on the enzymatic …

The E. coli BMT-4D/1A cells have been selected according to Munch-Petersen et al. They
carry two regulatory mutations (cytR and deoR) and are able to synthesize constitutively …

A wide range of natural purine analogues was used as probe to assess the mechanism of
recognition by the wild‐type (WT) E. coli purine nucleoside phosphorylase (PNP) versus its …

In recent years, enzymatic methodology has become a standard technique for the synthesis
of a wide variety of enantiomerically pure precursors and target molecules. Reports on …

A possibility of the one-pot synthesis of purine and pyrimidine nucleosides employing pure
recombinant ribokinase, phosphopentomutase and nucleoside phosphorylases in a …

Abstract Treatment of O2, 3′-anhydro-5′-O-trityl derivatives of thymidine (1) and 2′-
deoxyuridine (2) with lithium azide in dimethylformamide at 150° C resulted in the formation …

The biotechnological method of synthesis of ribavirin, vidarabin, and 6-azauridine by the use
of immobilized recombinant enzymatic preparations of nucleoside phosphorylase was …

A number of new 5, 6-disubstituted benzimidazoles have been prepared and their substrate
properties for recombinant E. coli purine nucleoside phosphorylase (PNP; the product of the …

Some recent findings in the biotechnology of biologically important nucleosides will be
discussed, viz.,(i) a new strategy of the cascade one-pot transformation of D-pentoses into …