The innovative potential of selenium-containing agents for fighting cancer and viral infections
Selenium-containing compounds have emerged as a potentially promising treatment for
viral infections and tumor development and dissemination. Selenium per se is often …
viral infections and tumor development and dissemination. Selenium per se is often …
Critical review of synthesis, toxicology and detection of acyclovir
YP Wei, LY Yao, YY Wu, X Liu, LH Peng, YL Tian… - Molecules, 2021 - mdpi.com
Acyclovir (ACV) is an effective and selective antiviral drug, and the study of its toxicology and
the use of appropriate detection techniques to control its toxicity at safe levels are extremely …
the use of appropriate detection techniques to control its toxicity at safe levels are extremely …
Selenization of Small Molecule Drugs: A New Player on the Board
There is an urgent need to develop safer and more effective modalities for the treatment of a
wide range of pathologies due to the increasing rates of drug resistance, undesired side …
wide range of pathologies due to the increasing rates of drug resistance, undesired side …
Optimized biocatalytic synthesis of 2‐selenopyrimidine nucleosides by transglycosylation
KF Hellendahl, F Kaspar, X Zhou, Z Yang… - …, 2021 - Wiley Online Library
Selenium‐modified nucleosides are powerful tools to study the structure and function of
nucleic acids and their protein interactions. The widespread application of 2 …
nucleic acids and their protein interactions. The widespread application of 2 …
Selenium compounds as promising antiviral agents
VK Jain, KI Priyadarsini - New Journal of Chemistry, 2024 - pubs.rsc.org
The past two decades of this century have faced half a dozen pandemics caused by different
kinds of viruses, affecting millions of people globally. Among them three zoonotic viruses of …
kinds of viruses, affecting millions of people globally. Among them three zoonotic viruses of …
Synthesis of 6-Selanyl-2-triazolylpurine Derivatives Using 2, 6-Bistriazolylpurines as Starting Materials
A Ritere, A Jeminejs, E Bizde̅na, M Turks… - ACS …, 2024 - ACS Publications
Two pathways toward 6-selanyl-2-triazolylpurine derivatives were designed. The first
method involved the synthesis of 2-chloro-6-selanylpurine derivatives, further SNAr reaction …
method involved the synthesis of 2-chloro-6-selanylpurine derivatives, further SNAr reaction …
Bioactive organoselenium compounds and therapeutic perspectives
After 1984, when ebselen was tested as a mimetic of the key antioxidant enzyme glutathione
peroxidase (GPx), a plethora of organoselenium compounds have been synthesized and …
peroxidase (GPx), a plethora of organoselenium compounds have been synthesized and …
An efficient and practical method for the selective synthesis of sodium diselenide and diorganyl diselenides through selenium reduction
YJ Lim, NH Shin, C Kim, YE Kim, H Cho, MS Park… - Tetrahedron, 2020 - Elsevier
Studies on an efficient and practical method for the selective synthesis of diorganyl
diselenides over diorganyl selenides are presented. Considering the discrepancies …
diselenides over diorganyl selenides are presented. Considering the discrepancies …
Recent Advances in the Synthesis of Acyclic Nucleosides and Their Therapeutic Applications
S Kumar, A Arora, R Chaudhary, R Kumar… - Topics in Current …, 2024 - Springer
DNA is commonly known as the “molecule of life” because it holds the genetic instructions
for all living organisms on Earth. The utilization of modified nucleosides holds the potential …
for all living organisms on Earth. The utilization of modified nucleosides holds the potential …
The Fight against Human Viruses: How NMR Can Help?
M Vincenzi, M Leone - Current Medicinal Chemistry, 2021 - benthamdirect.com
Background: COVID-19 has brought the world to its knees, and there is an urgent need for
new strategies to identify molecules capable of fighting the pandemic. During the last few …
new strategies to identify molecules capable of fighting the pandemic. During the last few …