Recent highlights of research on miRNAs as early potential biomarkers for cardiovascular complications of type 2 diabetes mellitus

A Bielska, M Niemira, A Kretowski - International Journal of Molecular …, 2021 - mdpi.com
Type 2 diabetes mellitus (T2DM) and its complications pose a serious threat to the life and
health of patients around the world. The most dangerous complications of this disease are …

The role of androgen receptor and microRNA interactions in androgen-dependent diseases

A Bielska, A Skwarska, A Kretowski… - International journal of …, 2022 - mdpi.com
The androgen receptor (AR) is a member of the steroid hormone receptor family of nuclear
transcription factors. It is present in the primary/secondary sexual organs, kidneys, skeletal …

Type 2 Diabetes Mellitus and its comorbidity, Alzheimer's disease: Identifying critical microRNA using machine learning

H Alamro, V Bajic, MT Macvanin, ER Isenovic… - Frontiers in …, 2023 - frontiersin.org
MicroRNAs (miRNAs) are critical regulators of gene expression in healthy and diseased
states, and numerous studies have established their tremendous potential as a tool for …

A Survey on Evolutionary Computation for Identifying Biomarkers of Complex Disease

J Liang, Z Hu, Y Bi, H Cheng, K Yu… - IEEE Transactions …, 2024 - ieeexplore.ieee.org
Biological markers (ie, biomarkers) is the key to predicting disease states and revealing the
molecular mechanisms in precision medicine of complex disease (eg, cancer). With the …

[HTML][HTML] MicroRNA signature for interpretable breast cancer classification with subtype clue

P Andreini, S Bonechi, M Bianchini, F Geraci - Journal of Computational …, 2022 - Elsevier
MicroRNAs (miRNAs) are short non-coding RNAs engaged in cellular regulation by
suppressing genes at their post-transcriptional stage. Evidence of their involvement in breast …

Circulating serum miR-362-3p and miR-6721-5p as potential biomarkers for classification patients with adult-type diffuse glioma

M Niemira, A Bielska, K Chwialkowska… - Frontiers in Molecular …, 2024 - frontiersin.org
According to the fifth edition of the WHO Classification of Tumours of the Central Nervous
System (CNS) published in 2021, grade 4 gliomas classification includes IDH-mutant …

The Expression Patterns of BECN1, LAMP2, and PINK1 Genes in Colorectal Cancer Are Potentially Regulated by Micrornas and CpG Islands: An In Silico Study

M Bednarczyk, E Fatyga… - Journal of Clinical …, 2020 - mdpi.com
Background: Autophagy plays a dual role of tumor suppression and tumor promotion in
colorectal cancer. The study aimed to find those microRNAs (miRNAs) important in BECN1 …

Expression of microRNA-27b in type 2 diabetic patients and relation to microvascular complications

YM Ghanem, EY Moursy, ET Elsayed… - Alexandria Journal of …, 2024 - Taylor & Francis
In this study, we aimed to explore whether circulating microRNA-27b (miR-27b) is affected in
diabetic patient with microvascular complications Methods This study was conducted on 90 …

Leveraging proteomics in orphan disease research: Pitfalls and potential

D Braconi, G Bernardini, O Spiga… - Expert Review of …, 2021 - Taylor & Francis
Introduction: The term 'orphan diseases' includes conditions meeting prevalence-based or
commercial viability criteria: they affect a small number of individuals and are considered an …

Development of diagnostic and prognostic molecular biomarkers in hepatocellular carcinoma using machine learning: A systematic review

A Brar, A Zhu, C Baciu, D Sharma, W Xu… - Liver Cancer …, 2022 - Wiley Online Library
Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related mortality and
morbidity worldwide. Machine learning (ML) tools have been developed in recent years to …