[HTML][HTML] Epileptic-network-based prediction and control of seizures in humans
Epilepsy is now conceptualized as a network disease. The epileptic brain network
comprises structurally and functionally connected cortical and subcortical brain regions …
comprises structurally and functionally connected cortical and subcortical brain regions …
Mapping lesion-related epilepsy to a human brain network
Importance It remains unclear why lesions in some locations cause epilepsy while others do
not. Identifying the brain regions or networks associated with epilepsy by mapping these …
not. Identifying the brain regions or networks associated with epilepsy by mapping these …
Closed-loop stimulation in periods with less epileptiform activity drives improved epilepsy outcomes
In patients with drug-resistant epilepsy, electrical stimulation of the brain in response to
epileptiform activity can make seizures less frequent and debilitating. This therapy, known as …
epileptiform activity can make seizures less frequent and debilitating. This therapy, known as …
Revisiting the concept of drug‐resistant epilepsy: a TASK1 report of the ILAE/AES Joint Translational Task Force
S Auvin, AS Galanopoulou, SL Moshé, H Potschka… - …, 2023 - Wiley Online Library
Despite progress in the development of anti‐seizure medications (ASMs), one third of
people with epilepsy have drug‐resistant epilepsy (DRE). The working definition of DRE …
people with epilepsy have drug‐resistant epilepsy (DRE). The working definition of DRE …
Intracranial EEG structure-function coupling and seizure outcomes after epilepsy surgery
Background and Objectives Surgery is an effective treatment for drug-resistant epilepsy,
which modifies the brain's structure and networks to regulate seizure activity. Our objective …
which modifies the brain's structure and networks to regulate seizure activity. Our objective …
[HTML][HTML] Generalisability of epileptiform patterns across time and patients
H Karimi-Rouzbahani, A McGonigal - Scientific Reports, 2024 - nature.com
The complexity of localising the epileptogenic zone (EZ) contributes to surgical resection
failures in achieving seizure freedom. The distinct patterns of epileptiform activity during …
failures in achieving seizure freedom. The distinct patterns of epileptiform activity during …
[HTML][HTML] Reproducible network changes occur in a mouse model of temporal lobe epilepsy but do not correlate with disease severity
Studying the development of brain network disruptions in epilepsy is challenged by the
paucity of data before epilepsy onset. Here, we used the unilateral, kainate mouse model of …
paucity of data before epilepsy onset. Here, we used the unilateral, kainate mouse model of …
Atypical connectome topography and signal flow in temporal lobe epilepsy
Temporal lobe epilepsy (TLE) is the most common pharmaco-resistant epilepsy in adults.
While primarily associated with mesiotemporal pathology, recent evidence suggests that …
While primarily associated with mesiotemporal pathology, recent evidence suggests that …
[HTML][HTML] Physiological and pathological neuronal connectivity in the living human brain based on intracranial EEG signals: the current state of research
Y Novitskaya, M Dümpelmann… - Frontiers in Network …, 2023 - frontiersin.org
Over the past decades, studies of human brain networks have received growing attention as
the assessment and modelling of connectivity in the brain is a topic of high impact with …
the assessment and modelling of connectivity in the brain is a topic of high impact with …
[HTML][HTML] Alterations in brain network functional connectivity and topological properties in DRE patients
Y Ding, K Guo, J Li, Q Shan, Y Guo, M Chen… - Frontiers in …, 2023 - frontiersin.org
Objective The study aimed to find the difference in functional network topology on interictal
electroencephalographic (EEG) between patients with drug-resistant epilepsy (DRE) and …
electroencephalographic (EEG) between patients with drug-resistant epilepsy (DRE) and …