[HTML][HTML] Cancer epigenetic biomarkers in liquid biopsy for high incidence malignancies

C Palanca-Ballester, A Rodriguez-Casanova, S Torres… - Cancers, 2021 - mdpi.com
Simple Summary Apart from genetic changes, cancer is characterized by epigenetic
alterations, which indicate modifications in the DNA (such as DNA methylation) and histones …

[HTML][HTML] Epigenetic landscape of liquid biopsy in colorectal cancer

A Rodriguez-Casanova, N Costa-Fraga… - Frontiers in Cell and …, 2021 - frontiersin.org
Colorectal cancer (CRC) is one of the most common malignancies and is a major cause of
cancer-related deaths worldwide. Thus, there is a clinical need to improve early detection of …

[HTML][HTML] Cell-free circulating (tumor) DNA before surgery as a prognostic factor in non-metastatic colorectal cancer: a systematic review

SJ Schraa, KL van Rooijen, M Koopman, GR Vink… - Cancers, 2022 - mdpi.com
Simple Summary Patients with colorectal cancer without distant metastases are often cured
by surgical tumor resection. Follow-up is needed because of the risk of disease recurrence …

Roles of methylated DNA biomarkers in patients with colorectal cancer

Z Ma, M Williams, YY Cheng, WK Leung - Disease markers, 2019 - Wiley Online Library
Colorectal cancer (CRC) is a leading cancer globally; therefore, early diagnosis and
surveillance of this cancer are of paramount importance. Current methods of CRC diagnosis …

[HTML][HTML] The role of circulating biomarkers in the early detection of recurrent colorectal cancer following resection of liver metastases

S Pericleous, RH Bhogal… - Frontiers in Bioscience …, 2022 - imrpress.com
On a global scale, colorectal cancer (CRC) is currently the fourth most commonly diagnosed
cancer and despite progress in early diagnosis and treatment has the third highest mortality …

Hydrogen peroxide-producing NADPH oxidases and the promotion of migratory phenotypes in cancer

JL Meitzler, MM Konaté, JH Doroshow - Archives of biochemistry and …, 2019 - Elsevier
The cellular microenvironment plays a critical role in cancer initiation and progression.
Exposure to oxidative stress, specifically hydrogen peroxide (H 2 O 2), has been linked to …

[HTML][HTML] The use of circulating tumor DNA for prognosis of gastrointestinal cancers

H Saluja, CS Karapetis, SK Pedersen, GP Young… - Frontiers in …, 2018 - frontiersin.org
Gastrointestinal cancers, including oesophageal, gastric and colorectal cancers (CRC) have
high rates of disease recurrence despite curative resection. There are a number of recent …

[HTML][HTML] Colorectal cancer biomarkers-a new trend in early diagnosis

SC TOMA, BS UNGUREANU… - Current Health …, 2018 - ncbi.nlm.nih.gov
Colorectal cancer (CRC) is one of the most widespread malignancy, posing as a great
challenge due to its high incidence and mortality in both genders. Yet, it also stands as one …

Potential of RASSF1A promoter methylation as a biomarker for colorectal cancer: Meta-analysis and TCGA analysis

F Hu, L Chen, MY Bi, L Zheng, JX He, YZ Huang… - … -Research and Practice, 2020 - Elsevier
The RAS association domain family protein 1A (RASSF1A) is a tumor suppressor in
colorectal cancer (CRC), and is often inactived by hypermethylation. Therefore, we …

Correlation between RASSF1A Methylation in Cell‐Free DNA and the Prognosis of Cancer Patients: A Systematic Review and Meta‐Analysis

S Chen, H Duan, D Zhang, G Sun - Journal of Oncology, 2022 - Wiley Online Library
Background. Although the effects of methylation of the Ras association domain‐containing
protein 1 isoform A (RASSF1A) gene in cell‐free DNA on the outcomes of patients with …