Comparison of Commonly Used and New Methods to Determine Small Molecule Non-Specific Binding to Human Liver Microsomes

T Wang, A Whitcher-Johnstone, YS Scaringella… - Journal of …, 2024 - Elsevier
Accurate measurement of non-specific binding of a drug candidate to human liver
microsomes (HLM) can be critical for the accurate determination of key enzyme kinetic …