Scaling up genetic circuit design for cellular computing: advances and prospects
Synthetic biology aims to engineer and redesign biological systems for useful real-world
applications in biomanufacturing, biosensing and biotherapy following a typical design-build …
applications in biomanufacturing, biosensing and biotherapy following a typical design-build …
Cell-free synthetic biology platform for engineering synthetic biological circuits and systems
Synthetic biology integrates diverse engineering disciplines to create novel biological
systems for biomedical and technological applications. The substantial growth of the …
systems for biomedical and technological applications. The substantial growth of the …
Deep learning to predict the lab-of-origin of engineered DNA
AAK Nielsen, CA Voigt - Nature communications, 2018 - nature.com
Genetic engineering projects are rapidly growing in scale and complexity, driven by new
tools to design and construct DNA. There is increasing concern that widened access to …
tools to design and construct DNA. There is increasing concern that widened access to …
Cell-free protein synthesis as a prototyping platform for mammalian synthetic biology
MB Kopniczky, C Canavan, DW McClymont… - ACS synthetic …, 2020 - ACS Publications
The field of mammalian synthetic biology is expanding quickly, and technologies for
engineering large synthetic gene circuits are increasingly accessible. However, for …
engineering large synthetic gene circuits are increasingly accessible. However, for …
GOLDBAR: A Framework for Combinatorial Biological Design
With the rise of new DNA part libraries and technologies for assembling DNA, synthetic
biologists are increasingly constructing and screening combinatorial libraries to optimize …
biologists are increasingly constructing and screening combinatorial libraries to optimize …
Engineered living conductive biofilms as functional materials
Natural living conductive biofilms transport electrons between electrodes and cells, as well
as among cells fixed within the film, catalyzing an array of reactions from acetate oxidation to …
as among cells fixed within the film, catalyzing an array of reactions from acetate oxidation to …
Automated robotic liquid handling assembly of modular DNA devices
Recent advances in modular DNA assembly techniques have enabled synthetic biologists to
test significantly more of the available" design space" represented by" devices" created as …
test significantly more of the available" design space" represented by" devices" created as …
A synthetic distributed genetic multi-bit counter
A design for genetically encoded counters is proposed via repressor-based circuits. An N-bit
counter reads sequences of input pulses and displays the total number of pulses, modulo 2 …
counter reads sequences of input pulses and displays the total number of pulses, modulo 2 …
Boosting secondary metabolite production and discovery through the engineering of novel microbial biosensors
UA de Frias, GKB Pereira… - BioMed research …, 2018 - Wiley Online Library
Bacteria are a source of a large number of secondary metabolites with several biomedical
and biotechnological applications. In recent years, there has been tremendous progress in …
and biotechnological applications. In recent years, there has been tremendous progress in …
Characterization of Programmable Transcription Activators in the Model Monocot Setaria viridis Via Protoplast Transfection
A Sychla, JA Casas-Mollano, MH Zinselmeier… - … : Methods and Protocols, 2022 - Springer
Recent advances in DNA synthesis and assembly allow for genetic constructs to be
designed and constructed in high throughput. Characterizing large numbers of variant …
designed and constructed in high throughput. Characterizing large numbers of variant …