Synthesis, molecular modelling studies and ADME prediction of benzothiazole clubbed oxadiazole-Mannich bases, and evaluation of their anti-diabetic activity …
A small library of new benzothiazole clubbed oxadiazole-Mannich bases (M-1 to M-22) were
synthesized and characterized by IR, NMR, Mass and Elemental analysis results. Molecular …
synthesized and characterized by IR, NMR, Mass and Elemental analysis results. Molecular …
[PDF][PDF] Benzothiazole-Versatile heterocyclic nucleus in medicinal chemistry: A review
GN Raju, BS Karumudi, NR Rao - Int. J. Pharm. Chem, 2015 - Citeseer
Benzothiazole, the bicyclic ring system consists of thiazole ring fused with benzene ring.
Benzothiazole moiety is very small but is fascinated by scientists because of the different …
Benzothiazole moiety is very small but is fascinated by scientists because of the different …
[HTML][HTML] Design, synthesis, molecular docking and anticonvulsant evaluation of novel 6-iodo-2-phenyl-3-substituted-quinazolin-4 (3H)-ones
MK Ibrahim, K El-Adl, AA Al-Karmalawy - Bulletin of Faculty of Pharmacy …, 2015 - Elsevier
A new series of 6-iodo-2-phenyl-3-substituted-quinazolin-4 (3H)-one (5–12 a–b) derivatives
were synthesized, evaluated for their anticonvulsant activity against pentylenetetrazole …
were synthesized, evaluated for their anticonvulsant activity against pentylenetetrazole …
State of the art review and report of new tool for drug discovery
Y Martinez-Lopez, Y Caballero… - Current topics in …, 2017 - ingentaconnect.com
Background: There are a great number of tools that can be used in QSAR/QSPR studies;
they are implemented in several programs that are reviewed in this report. The usefulness of …
they are implemented in several programs that are reviewed in this report. The usefulness of …
Synthesis, modelling, and anticonvulsant studies of new quinazolines showing three highly active compounds with low toxicity and high affinity to the GABA-A receptor
Some novel fluorinated quinazolines (5a–j) were designed and synthesized to be evaluated
for their anticonvulsant activity and their neurotoxicity. Structures of all newly synthesized …
for their anticonvulsant activity and their neurotoxicity. Structures of all newly synthesized …
[PDF][PDF] Molecular docking, synthesis and biological evaluation of some novel 2-substituted-3-allyl-4 (3H)-quinazolinone derivatives as anticonvulsant agents
HS Abulkhair, KM El-Gamal, K El-Adl, MF Fadl - Med. Chem, 2016 - researchgate.net
A new series of 2-substituted-3-allyl-4 (3H)-quinazolinone derivatives (4a-e-8a-d) were
synthesized and evaluated for their anticonvulsant activity against pentylenetetrazole (PTZ) …
synthesized and evaluated for their anticonvulsant activity against pentylenetetrazole (PTZ) …
Unveiling the Anti-convulsant Potential of Novel Series of 1, 2, 4-Triazine-6H-Indolo [2, 3-b] quinoline Derivatives: In Silico Molecular Docking, ADMET, DFT, and …
H Singh, D Pathak - Current Computer-Aided Drug Design, 2024 - ingentaconnect.com
Background: Epilepsy is a chronic neurological disorder caused by irregular electrical
activity in the brain. To manage this disorder effectively, it is imperative to identify potential …
activity in the brain. To manage this disorder effectively, it is imperative to identify potential …
Synthesis, molecular docking, and biological evaluation of some novel 2-(5-substituted 1, 3, 4-oxadiazole-2-yl)-1, 3-benzothiazole Derivatives as Anticonvulsant …
Background: Benzothiazole is an organosulfur heterocyclic compound that has a
considerable place in drug discovery due to significant pharmacological actions. Objective …
considerable place in drug discovery due to significant pharmacological actions. Objective …
A Mini Review on Recent Advancements in the Therapeutic Potentials of Benzothiazoles
Among the various fused heterocyclic rings, benzothiazole and its analogs have been
explored broadly in search of newer therapeutic medicinal agents. The benzothiazole …
explored broadly in search of newer therapeutic medicinal agents. The benzothiazole …
[PDF][PDF] A Review: Synthesis and Pharmacological Profile of [1, 5]-Benzothiazepine
S Khasimbi, F Ali, SW Kumari Neha… - Letters in Organic …, 2020 - researchgate.net
The 1, 5-benzothiazepine derivatives are of particular interest for lead discovery since they
have been found active against different families of targets. 1, 5-Benzothaizepines …
have been found active against different families of targets. 1, 5-Benzothaizepines …