Vulvovaginal candidiasis (VVC) is an infection caused by Candida species that affects
millions of women every year. Although Candida albicans is the main cause of VVC, the …

Summary Mannose‐binding lectin (MBL), collectin‐10, collectin‐11, and the ficolins (ficolin‐
1, ficolin‐2, and ficolin‐3) are soluble pattern recognition molecules in the lectin complement …

The humoral arm of innate immunity includes diverse molecules with antibody-like functions,
some of which serve as disease severity biomarkers in coronavirus disease 2019 (COVID …

The complement system comprises several fluid-phase and membrane-associated proteins.
Under physiological conditions, activation of the fluid-phase components of complement is …

Idiopathic pulmonary fibrosis (IPF) is a lethal scarring lung disease that affects older adults.
Heterozygous rare mutations in the genes encoding telomerase are found in∼ 15% of …

Mannose-binding lectin (MBL) is a pattern recognition molecule of the innate immune
system. It belongs to the collectin family of proteins in which lectin (carbohydrate …

Some proteins we now regard as animal lectins were discovered before plant lectins, though
many were not recognised as carbohydrate-binding proteins for many years after first being …

The complement system comprises a complex array of enzymes and non-enzymatic proteins
that is essential for the operation of the innate as well as the adaptive immune defence1 …

Innate immunity is the earliest response to invading microbes and acts to contain infection in
the first minutes to hours of challenge. Unlike adaptive immunity that relies upon clonal …

Mannose-binding lectin (MBL) is a collagenous serum lectin believed to be of importance in
innate immunity. Genetically determined low levels of the protein are known to predispose to …