Older adult participation in cancer clinical trials: a systematic review of barriers and interventions

MS Sedrak, RA Freedman, HJ Cohen… - CA: a cancer journal …, 2021 - Wiley Online Library
Cancer is a disease of aging and, as the world's population ages, the number of older
persons with cancer is increasing and will make up a growing share of the oncology …

Updated recommendations regarding the management of older patients with breast cancer: a joint paper from the European Society of Breast Cancer Specialists …

L Biganzoli, NML Battisti, H Wildiers… - The Lancet …, 2021 - thelancet.com
Breast cancer is increasingly prevalent in older adults and is a substantial part of routine
oncology practice. However, management of breast cancer in this population is challenging …

Geriatric assessment–driven intervention (GAIN) on chemotherapy-related toxic effects in older adults with cancer: a randomized clinical trial

D Li, CL Sun, H Kim, E Soto-Perez-de-Celis… - JAMA …, 2021 - jamanetwork.com
Importance Although geriatric assessment–driven intervention improves patient-centered
outcomes, its influence on chemotherapy-related toxic effects remains unknown. Objective …

Practical assessment and management of vulnerabilities in older patients receiving systemic cancer therapy: ASCO guideline update

W Dale, HD Klepin, GR Williams… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE To update the ASCO guideline (2018) on the practical assessment and
management of age-associated vulnerabilities in older patients undergoing systemic cancer …

[HTML][HTML] Practical assessment and management of vulnerabilities in older patients receiving chemotherapy: ASCO guideline for geriatric oncology

SG Mohile, W Dale, MR Somerfield… - Journal of Clinical …, 2018 - ncbi.nlm.nih.gov
Purpose To provide guidance regarding the practical assessment and management of
vulnerabilities in older patients undergoing chemotherapy. Methods An Expert Panel was …

NCCN guidelines® insights: older adult oncology, version 1.2021: featured updates to the NCCN guidelines

E Dotan, LC Walter, IS Browner, K Clifton… - Journal of the National …, 2021 - jnccn.org
The NCCN Guidelines for Older Adult Oncology address specific issues related to the
management of cancer in older adults, including screening and comprehensive geriatric …

[HTML][HTML] Relationship between markers of malnutrition and clinical outcomes in older adults with cancer: systematic review, narrative synthesis and meta-analysis

AF Bullock, SL Greenley, GAG McKenzie… - European journal of …, 2020 - nature.com
Malnutrition predicts poorer clinical outcomes for people with cancer. Older adults with
cancer are a complex, growing population at high risk of weight-losing conditions. A number …

Frailty and cancer: implications for oncology surgery, medical oncology, and radiation oncology

CG Ethun, MA Bilen, AB Jani, SK Maithel… - CA: a cancer journal …, 2017 - Wiley Online Library
Answer questions and earn CME/CNE The concept of frailty has become increasingly
recognized as one of the most important issues in health care and health outcomes and is of …

Functional versus chronological age: geriatric assessments to guide decision making in older patients with cancer

E Soto-Perez-de-Celis, D Li, Y Yuan, YM Lau… - The Lancet …, 2018 - thelancet.com
As the worldwide population ages, oncologists are often required to make difficult and
complex decisions regarding the treatment of older people (aged 65 years and older) with …

[HTML][HTML] Validation of a prediction tool for chemotherapy toxicity in older adults with cancer

A Hurria, S Mohile, A Gajra, H Klepin… - Journal of Clinical …, 2016 - ncbi.nlm.nih.gov
Purpose Older adults are at increased risk for chemotherapy toxicity, and standard oncology
assessment measures cannot identify those at risk. A predictive model for chemotherapy …