Adherence to antiplatelet treatment with P2Y12 receptor inhibitors. Is there anything we can do to improve it? A systematic review of randomized trials
A Kubica, K Obońska, T Fabiszak… - Current medical research …, 2016 - Taylor & Francis
Antiplatelet therapy is the cornerstone of treatment for patients with acute coronary
syndromes (ACS) and/or undergoing percutaneous coronary interventions. Non-adherence …
syndromes (ACS) and/or undergoing percutaneous coronary interventions. Non-adherence …
Aspirin and clopidogrel resistance; a neglected gap in stroke and cardiovascular practice in Iran: a systematic review and meta-analysis
M Parsa-Kondelaji, H Mansouritorghabeh - Thrombosis Journal, 2023 - Springer
Objective Antiplatelet drugs, such as Aspirin and Clopidogrel (Plavix) are effective in the
primary prevention of thromboembolic events. They are commonly used to reduce the risk of …
primary prevention of thromboembolic events. They are commonly used to reduce the risk of …
Pharmacokinetic, pharmacodynamic, and pharmacogenetic assays to monitor clopidogrel therapy
BY Alvitigala, LV Gooneratne… - Pharmacology …, 2020 - Wiley Online Library
Clopidogrel is the most common and widely used antiplatelet agent for patients with
coronary artery disease following confirmation by electrocardiographic studies. The …
coronary artery disease following confirmation by electrocardiographic studies. The …
Pharmacodynamic properties of antiplatelet agents: current knowledge and future perspectives
KI Kalantzi, ME Tsoumani, IA Goudevenos… - Expert review of …, 2012 - Taylor & Francis
Platelets play an important role in atherothrombotic disease. The currently available
antiplatelet drugs target key steps of platelet activation including thromboxane A2 synthesis …
antiplatelet drugs target key steps of platelet activation including thromboxane A2 synthesis …
[HTML][HTML] The effects of CYP2C19 genotype polymorphism and clopidogrel resistance on ischemic event occurrence in patients with peripheral arterial disease …
Y Zhang, Q Ran, K Yin, Y Wang, J Liu, Y Zong… - Thrombosis …, 2024 - Elsevier
Introduction Peripheral arterial disease (PAD) affects approximately 236 million people
worldwide. Therefore, this study aimed to investigate the relationship between CYP2C19 …
worldwide. Therefore, this study aimed to investigate the relationship between CYP2C19 …
Standard vs. modified antiplatelet therapy based on thromboelastography with platelet mapping for preventing bleeding events in patients undergoing stent-assisted …
Y Li, X Zhang, Z Guo, J Zhu, R Xu, Z He… - Frontiers in …, 2021 - frontiersin.org
Background and Purpose: Stent-assisted coiling (SAC) of intracranial aneurysms is usually
treated with antiplatelet therapy to reduce the risk of postoperative ischemic events …
treated with antiplatelet therapy to reduce the risk of postoperative ischemic events …
Assessing the efficacy of VerifyNow platelet-function testing in predicting postoperative thromboembolic complications of neuroendovascular surgery: A systematic …
DL Mitchell, LS McGuire, SI Khalid… - Interventional …, 2024 - journals.sagepub.com
Background Despite the heavily debated use of routine platelet-function testing, the
VerifyNow Platelet Reactivity Unit (PRU) assay has been increasingly adopted as standard …
VerifyNow Platelet Reactivity Unit (PRU) assay has been increasingly adopted as standard …
The CYP2C19*2 and CYP2C19*17 Polymorphisms play a Vital Role in Clopidogrel Responsiveness after Percutaneous Coronary Intervention: A …
Clopidogrel inhibits platelet activation and aggregation by blocking the P2Y12 receptor.
Dual antiplatelet therapy with clopidogrel and aspirin is recommended treatment by current …
Dual antiplatelet therapy with clopidogrel and aspirin is recommended treatment by current …
Gene polymorphism of cytochrome P450 2C19* 2 and clopidogrel resistance reflected by platelet function assays: a meta-analysis
X Hou, J Shi, H Sun - European journal of clinical pharmacology, 2014 - Springer
Background The relationship between CYP2C19* 2 gene polymorphism and clopidogrel
resistance reflected by platelet function assays has been studied extensively in the past …
resistance reflected by platelet function assays has been studied extensively in the past …
Platelets: still a therapeutical target for haemostatic disorders
Platelets are cytoplasmatic fragments from bone marrow megakaryocytes present in blood.
In this work, we review the basis of platelet mechanisms, their participation in syndromes …
In this work, we review the basis of platelet mechanisms, their participation in syndromes …