Adipose tissue plays essential roles in maintaining lipid and glucose homeostasis. To date
several types of adipose tissue have been identified, namely white, brown, and beige, that …

Background Metformin is the most widely prescribed drug to lower glucose and has a
definitive effect on the cardiovascular system. The goal of this systematic review and meta …

Background Diabetes and elevated blood glucose have been associated with increased risk
of atrial fibrillation in a number of epidemiological studies, however, the findings have not …

Type 2 diabetes mellitus (T2DM) is a worldwide major health burden and heart failure (HF)
is the most common cardiovascular (CV) complication in affected patients. Therefore …

Background Metformin is a widely used first-line drug for treatment of type 2 diabetes.
Despite its advantages, metformin has variable therapeutic effects, contraindications, and …

Adipose tissue is a critical regulator of systemic metabolism and bodily homeostasis as it
secretes a myriad of adipokines, including inflammatory and anti-inflammatory cytokines. As …

Aim Pharmacologic therapy for T2DM has proven benefits in terms of reducing elevated
blood glucose levels and reducing microvascular complications. However, the impact of …

Management guidelines continue to identify metformin as initial pharmacologic antidiabetic
therapy of choice for people with type 2 diabetes without contraindications, despite recent …

Background: Metformin is first-line therapy for type 2 diabetes mellitus, although its effects on
the cardiovascular system are unproved. Methods: In this post hoc analysis, patients in …

Alzheimer's disease (AD) is the most common neurodegenerative disease, which results in
dementia typically in the elderly. The disease is mainly characterized by the deposition of …