[HTML][HTML] Targeting necroptosis: a novel therapeutic option for retinal degenerative diseases

Q Zhang, X Hu, W Zhao, X Ban, Y Li… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
The discovery of the necroptosis, a form of regulated necrosis that is mediated by receptor-
interacting protein kinase 1 (RIPK1), RIPK3, and mixed-lineage kinase domain-like …

Post-traumatic infectious endophthalmitis

N Bhagat, S Nagori, M Zarbin - Survey of ophthalmology, 2011 - Elsevier
Post-traumatic endophthalmitis is an uncommon yet devastating complication of an open
globe injury. Risk factors include presence of an intraocular foreign body (IOFB), lens …

Advances in development of exosomes for ophthalmic therapeutics

Y Tian, T Zhang, J Li, Y Tao - Advanced Drug Delivery Reviews, 2023 - Elsevier
Exosomes contain multiple bioactive molecules and maintain the connection between cells.
Recent advances in exosome-based therapeutics have witnessed unprecedented …

[HTML][HTML] The cereus matter of Bacillus endophthalmitis

MH Mursalin, ET Livingston, MC Callegan - Experimental Eye Research, 2020 - Elsevier
Bacillus cereus (B. cereus) endophthalmitis is a devastating intraocular infection primarily
associated with post-traumatic injuries. The majority of these infections result in substantial …

[HTML][HTML] The ocular trauma score

R Scott - Community eye health, 2015 - ncbi.nlm.nih.gov
1 On first examination, assign an initial raw score based on the initial visual acuity (VA)–see
A in Table 1. For example, for perception of light (PL) or hand movements (HM) 70 raw …

[图书][B] Trauma care manual

I Greaves, K Porter, J Garner - 2021 - taylorfrancis.com
The Trauma Care Manual 3e is the definitive evidence-based manual of best trauma
practice. Now in its third edition, this valuable book continues to provide clear practical …

Effect of time to primary repair on final visual outcome after open globe injury

RJ Blanch, J Bishop, H Javidi, PI Murray - British Journal of …, 2019 - bjo.bmj.com
Background/Aim Historic data suggest that open globe injuries should be repaired within 12–
24 hours to reduce the risk of endophthalmitis. However, endophthalmitis is uncommon …

Effects of intravitreal injection of siRNA against caspase-2 on retinal and optic nerve degeneration in air blast induced ocular trauma

CN Thomas, A Bernardo-Colón, E Courtie, G Essex… - Scientific reports, 2021 - nature.com
Ocular repeated air blast injuries occur from low overpressure blast wave exposure, which
are often repeated and in quick succession. We have shown that caspase-2 caused the …

Afferent visual manifestations of traumatic brain injury

NH Saliman, A Belli, RJ Blanch - Journal of neurotrauma, 2021 - liebertpub.com
Traumatic brain injury (TBI) causes structural and functional damage to the central nervous
system including the visual pathway. Defects in the afferent visual pathways affect visual …

Retinal ganglion cells die by necroptotic mechanisms in a site-specific manner in a rat blunt ocular injury model

CN Thomas, AM Thompson, Z Ahmed, RJ Blanch - Cells, 2019 - mdpi.com
Closed-globe injury can cause visual loss in military and civilian populations, with retinal cell
death, including retinal ganglion cell (RGC) degeneration, leading to irreversible blindness …