[HTML][HTML] Human placental development and function
T Cindrova-Davies, AN Sferruzzi-Perri - Seminars in cell & developmental …, 2022 - Elsevier
The placenta is a transient fetal organ that plays a critical role in the health and wellbeing of
both the fetus and its mother. Functionally, the placenta sustains the growth of the fetus as it …
both the fetus and its mother. Functionally, the placenta sustains the growth of the fetus as it …
[HTML][HTML] Oxidative stress and mitochondrial dysfunction in early-onset and late-onset preeclampsia
R Marín, DI Chiarello, C Abad, D Rojas… - … et Biophysica Acta (BBA …, 2020 - Elsevier
Preeclampsia is a pregnancy-specific syndrome with multisystem involvement which leads
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …
to foetal, neonatal, and maternal morbidity and mortality. This syndrome is characterized by …
Placental function in maternal obesity
Maternal obesity is associated with pregnancy complications and increases the risk for the
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
infant to develop obesity, diabetes and cardiovascular disease later in life. However, the …
Adaptations of the human placenta to hypoxia: opportunities for interventions in fetal growth restriction
BACKGROUND The placenta is the functional interface between the mother and the fetus
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
during pregnancy, and a critical determinant of fetal growth and life-long health. In the first …
Immunoendocrine dysregulation during gestational diabetes mellitus: The central role of the placenta
A Olmos-Ortiz, P Flores-Espinosa, L Díaz… - International Journal of …, 2021 - mdpi.com
Gestational Diabetes Mellitus (GDM) is a transitory metabolic condition caused by
dysregulation triggered by intolerance to carbohydrates, dysfunction of beta-pancreatic and …
dysregulation triggered by intolerance to carbohydrates, dysfunction of beta-pancreatic and …
[HTML][HTML] Placental energy metabolism in health and disease—significance of development and implications for preeclampsia
ILMH Aye, CE Aiken, DS Charnock-Jones… - American journal of …, 2022 - Elsevier
The placenta is a highly metabolically active organ fulfilling the bioenergetic and
biosynthetic needs to support its own rapid growth and that of the fetus. Placental metabolic …
biosynthetic needs to support its own rapid growth and that of the fetus. Placental metabolic …
Placental mitochondria and reactive oxygen species in the physiology and pathophysiology of pregnancy
Mitochondria are central to cell function. The placenta forms the interface between maternal
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …
and fetal systems, and placental mitochondria have critical roles in maintaining pregnancy …
Maternal selenium deficiency during pregnancy in mice increases thyroid hormone concentrations, alters placental function and reduces fetal growth
Key points Inappropriate intake of key micronutrients in pregnancy is known to alter maternal
endocrine status, impair placental development and induce fetal growth restriction …
endocrine status, impair placental development and induce fetal growth restriction …
Hypoxia and mitochondrial dysfunction in pregnancy complications
Hypoxia is a common and severe stress to an organism's homeostatic mechanisms, and
hypoxia during gestation is associated with significantly increased incidence of maternal …
hypoxia during gestation is associated with significantly increased incidence of maternal …
Placental mitochondrial function and dysfunction in preeclampsia
The placenta is a vital organ of pregnancy, regulating adaptation to pregnancy, gestational
parent/fetal exchange, and ultimately, fetal development and growth. Not surprisingly, in …
parent/fetal exchange, and ultimately, fetal development and growth. Not surprisingly, in …