Obesity II: establishing causal links between chemical exposures and obesity
Obesity is a multifactorial disease with both genetic and environmental components. The
prevailing view is that obesity results from an imbalance between energy intake and …
prevailing view is that obesity results from an imbalance between energy intake and …
Early developmental conditioning of later health and disease: physiology or pathophysiology?
MA Hanson, PD Gluckman - Physiological reviews, 2014 - journals.physiology.org
Extensive experimental animal studies and epidemiological observations have shown that
environmental influences during early development affect the risk of later pathophysiological …
environmental influences during early development affect the risk of later pathophysiological …
Environmental obesogens: mechanisms and controversies
JJ Heindel, B Blumberg - Annual review of pharmacology and …, 2019 - annualreviews.org
Obesity is a worldwide pandemic in adults as well as children and adds greatly to health
care costs through its association with type 2 diabetes, metabolic syndrome, cardiovascular …
care costs through its association with type 2 diabetes, metabolic syndrome, cardiovascular …
Benchmarking organic micropollutants in wastewater, recycled water and drinking water with in vitro bioassays
Thousands of organic micropollutants and their transformation products occur in water.
Although often present at low concentrations, individual compounds contribute to mixture …
Although often present at low concentrations, individual compounds contribute to mixture …
Endocrine disruptors: from endocrine to metabolic disruption
C Casals-Casas, B Desvergne - Annual review of physiology, 2011 - annualreviews.org
Synthetic chemicals currently used in a variety of industrial and agricultural applications are
leading to widespread contamination of the environment. Even though the intended uses of …
leading to widespread contamination of the environment. Even though the intended uses of …
Role of environmental chemicals in diabetes and obesity: a National Toxicology Program workshop review
KA Thayer, JJ Heindel, JR Bucher… - Environmental health …, 2012 - ehp.niehs.nih.gov
Background: There has been increasing interest in the concept that exposures to
environmental chemicals may be contributing factors to the epidemics of diabetes and …
environmental chemicals may be contributing factors to the epidemics of diabetes and …
endocrine disrupting chemicals and immune responses: a focus on bisphenol-A and its potential mechanisms
Endocrine disrupting chemicals (EDCs) have become of concern for a variety f health
issues. Due to their effects on the endocrine system they have been thoroughly examined …
issues. Due to their effects on the endocrine system they have been thoroughly examined …
[HTML][HTML] Environmental obesogens and their impact on susceptibility to obesity: new mechanisms and chemicals
RJ Egusquiza, B Blumberg - Endocrinology, 2020 - academic.oup.com
The incidence of obesity has reached an all-time high, and this increase is observed
worldwide. There is a growing need to understand all the factors that contribute to obesity to …
worldwide. There is a growing need to understand all the factors that contribute to obesity to …
The retinoid X receptors and their ligands
MI Dawson, Z Xia - Biochimica et Biophysica Acta (BBA)-Molecular and …, 2012 - Elsevier
This chapter presents an overview of the current status of studies on the structural and
molecular biology of the retinoid X receptor subtypes α, β, and γ (RXRs, NR2B1–3), their …
molecular biology of the retinoid X receptor subtypes α, β, and γ (RXRs, NR2B1–3), their …
Structural and mechanistic insights into bisphenols action provide guidelines for risk assessment and discovery of bisphenol A substitutes
V Delfosse, M Grimaldi, JL Pons… - Proceedings of the …, 2012 - National Acad Sciences
Bisphenol A (BPA) is an industrial compound and a well known endocrine-disrupting
chemical with estrogenic activity. The widespread exposure of individuals to BPA is …
chemical with estrogenic activity. The widespread exposure of individuals to BPA is …