Although anticoagulants have been in use for more than 80 years, heparin and vitamin K
antagonists were the sole available options until recently. Although these agents …

A thrombus is a blood clot that forms in the lumen of an artery or vein, restricting blood flow
and causing clinical symptoms. Thrombosis is associated with many life‐threatening …

Ischemia superimposed upon pancreatic edema leads to acute necrotizing pancreatitis. One
possible mechanism contributing to ischemia is intravascular thrombogenesis since fibrin …

Antithrombotic drugs have some side effects, such as risk of serious bleeding. Development
of antithrombotic drugs that inhibit components of the intrinsic coagulation pathway and …

Fucosylated chondroitin sulfate (FCS) extracted from Phyllophorella kohkutiensis (PkFCS) is
composed of d-GalNAc, d-GlcA, l-Fuc and-SO 4 2−. According to the defined structures …

Chlorella is one of the most widely cultivated species of microalgae and has been
consumed as a “green healthy food”. In this study, a novel polysaccharide (CPP-1) was …

Glycosaminoglycans (GAGs) with unique structures from marine animals show intriguing
pharmacological activities and negligible biological risks, providing more options for us to …

Stichopus monotuberculatus is a tropical sea cucumber species and used as a folk medicine
and tonic food. In this study, a fucosylated glycosaminoglycan (SmFG), the depolymerized …

Laminaria japonica is widely consumed as a key food and medicine. Polysaccharides are
one of the most plentiful constituents of this marine plant. In this study, several …

A simple and sensitive fluorometric assay based on nitrogen-doped carbon dots (N-CDs)
was developed for the determination of thrombin (TB) activity in human serum samples and …