Ten steps to becoming a musculoskeletal simulation expert: a half-century of progress and outlook for the future

SD Uhlrich, TK Uchida, MR Lee, SL Delp - Journal of biomechanics, 2023 - Elsevier
Over the past half-century, musculoskeletal simulations have deepened our knowledge of
human and animal movement. This article outlines ten steps to becoming a musculoskeletal …

From fibre to function: are we accurately representing muscle architecture and performance?

J Charles, R Kissane, T Hoehfurtner… - Biological …, 2022 - Wiley Online Library
The size and arrangement of fibres play a determinate role in the kinetic and energetic
performance of muscles. Extrapolations between fibre architecture and performance …

Full-body musculoskeletal model for muscle-driven simulation of human gait

A Rajagopal, CL Dembia, MS DeMers… - IEEE transactions on …, 2016 - ieeexplore.ieee.org
Objective: Musculoskeletal models provide a noninvasive means to study human movement
and predict the effects of interventions on gait. Our goal was to create an open-source 3-D …

Predicting gait adaptations due to ankle plantarflexor muscle weakness and contracture using physics-based musculoskeletal simulations

CF Ong, T Geijtenbeek, JL Hicks… - PLoS computational …, 2019 - journals.plos.org
Deficits in the ankle plantarflexor muscles, such as weakness and contracture, occur
commonly in conditions such as cerebral palsy, stroke, muscular dystrophy, Charcot-Marie …

Simulating ideal assistive devices to reduce the metabolic cost of walking with heavy loads

CL Dembia, A Silder, TK Uchida, JL Hicks, SL Delp - PloS one, 2017 - journals.plos.org
Wearable robotic devices can restore and enhance mobility. There is growing interest in
designing devices that reduce the metabolic cost of walking; however, designers lack …

[HTML][HTML] TLEM 2.0–A comprehensive musculoskeletal geometry dataset for subject-specific modeling of lower extremity

V Carbone, R Fluit, P Pellikaan, MM Van Der Krogt… - Journal of …, 2015 - Elsevier
When analyzing complex biomechanical problems such as predicting the effects of
orthopedic surgery, subject-specific musculoskeletal models are essential to achieve …

[HTML][HTML] Generic scaled versus subject-specific models for the calculation of musculoskeletal loading in cerebral palsy gait: Effect of personalized musculoskeletal …

H Kainz, M Wesseling, I Jonkers - Clinical Biomechanics, 2021 - Elsevier
Background Musculoskeletal modelling is used to assess musculoskeletal loading during
gait. Linear scaling methods are used to personalize generic models to each participant's …

Multi-level personalization of neuromusculoskeletal models to estimate physiologically plausible knee joint contact forces in children

G Davico, DG Lloyd, CP Carty, BA Killen… - … and modeling in …, 2022 - Springer
Neuromusculoskeletal models are a powerful tool to investigate the internal biomechanics of
an individual. However, commonly used neuromusculoskeletal models are generated via …

Heterogeneity of muscle sizes in the lower limbs of children with cerebral palsy

GG Handsfield, CH Meyer, MF Abel… - Muscle & nerve, 2016 - Wiley Online Library
Introduction Cerebral palsy (CP) is associated with reduced muscle volumes, but previous
studies have reported deficits in only a small number of muscles. The extent of volume …

[HTML][HTML] Investigation of the dependence of joint contact forces on musculotendon parameters using a codified workflow for image-based modelling

L Modenese, E Montefiori, A Wang, S Wesarg… - Journal of …, 2018 - Elsevier
The generation of subject-specific musculoskeletal models of the lower limb has become a
feasible task thanks to improvements in medical imaging technology and musculoskeletal …