[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …
key parameters for estimating infectiousness. As shedding of infectious virus is required for …
The duration of infectiousness of individuals infected with SARS-CoV-2
KA Walsh, S Spillane, L Comber, K Cardwell… - Journal of Infection, 2020 - Elsevier
Objectives To summarise the evidence on the duration of infectiousness of individuals in
whom SARS-CoV-2 ribonucleic acid is detected. Methods A rapid review was undertaken in …
whom SARS-CoV-2 ribonucleic acid is detected. Methods A rapid review was undertaken in …
[HTML][HTML] Infectious viral load in unvaccinated and vaccinated individuals infected with ancestral, Delta or Omicron SARS-CoV-2
O Puhach, K Adea, N Hulo, P Sattonnet, C Genecand… - Nature medicine, 2022 - nature.com
Infectious viral load (VL) expelled as droplets and aerosols by infected individuals partly
determines transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
determines transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA. 5 Omicron variant in mice
SM Scheaffer, D Lee, B Whitener, B Ying, K Wu… - Nature medicine, 2023 - nature.com
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) …
in the Omicron lineage has resulted in diminished Coronavirus Disease 2019 (COVID-19) …
SARS-CoV-2 Omicron virus causes attenuated disease in mice and hamsters
PJ Halfmann, S Iida, K Iwatsuki-Horimoto, T Maemura… - Nature, 2022 - nature.com
The recent emergence of B. 1.1. 529, the Omicron variant,, has raised concerns of escape
from protection by vaccines and therapeutic antibodies. A key test for potential …
from protection by vaccines and therapeutic antibodies. A key test for potential …
Characterization and antiviral susceptibility of SARS-CoV-2 Omicron BA. 2
R Uraki, M Kiso, S Iida, M Imai, E Takashita, M Kuroda… - Nature, 2022 - nature.com
The recent emergence of SARS-CoV-2 Omicron (B. 1.1. 529 lineage) variants possessing
numerous mutations has raised concerns of decreased effectiveness of current vaccines …
numerous mutations has raised concerns of decreased effectiveness of current vaccines …
Neutralization, effector function and immune imprinting of Omicron variants
Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots
in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on …
in the receptor-binding domain (RBD) of the spike protein. The effects of these mutations on …
Escape of SARS-CoV-2 501Y. V2 from neutralization by convalescent plasma
SARS-CoV-2 variants of concern (VOC) have arisen independently at multiple locations,
and may reduce the efficacy of current vaccines that target the spike glycoprotein of SARS …
and may reduce the efficacy of current vaccines that target the spike glycoprotein of SARS …
Neutralizing and protective human monoclonal antibodies recognizing the N-terminal domain of the SARS-CoV-2 spike protein
N Suryadevara, S Shrihari, P Gilchuk, LA VanBlargan… - Cell, 2021 - cell.com
Most human monoclonal antibodies (mAbs) neutralizing SARS-CoV-2 recognize the spike
(S) protein receptor-binding domain and block virus interactions with the cellular receptor …
(S) protein receptor-binding domain and block virus interactions with the cellular receptor …
[HTML][HTML] Human neutralizing antibodies against SARS-CoV-2 require intact Fc effector functions for optimal therapeutic protection
SARS-CoV-2 has caused the global COVID-19 pandemic. Although passively delivered
neutralizing antibodies against SARS-CoV-2 show promise in clinical trials, their mechanism …
neutralizing antibodies against SARS-CoV-2 show promise in clinical trials, their mechanism …