The nuclear lamins are type V intermediate filament proteins that are critically important for
the structural properties of the nucleus. In addition, they are involved in the regulation of …

Nuclear lamins are intermediate filament-type proteins that are the major building blocks of
the nuclear lamina, a fibrous proteinaceous meshwork underlying the inner nuclear …

At the end of mitosis, the nuclear lamins assemble to form the nuclear lamina during nuclear
envelope formation in daughter cells. We have fused A-and B-type nuclear lamins to the …

The presence of a distinct nucleus, the compartment for confining the genome, transcription
and RNA maturation, is a central (and eponymous) feature that distinguishes eukaryotes …

Mitotic spindle morphogenesis is a series of highly coordinated movements that lead to
chromosome segregation and cytokinesis. We report that the intermediate filament protein …

Lamins interact with a host of nuclear membrane proteins, transcription factors, chromatin
regulators, signaling molecules, splicing factors, and even chromatin itself to form a nuclear …

The nuclear envelope (NE) is one of the least characterized structures of eukaryotic cells.
The study of its functional roles is hampered by the small number of proteins known to be …

Nuclear intermediate filament networks formed by A-and B-type lamins are major
components of the nucleoskeleton that are required for nuclear structure and function, with …

Lamin-associated polypeptides (LAPs) comprise inner nuclear membrane proteins tightly
associated with the peripheral lamin scaffold as well as proteins forming stable complexes …

The lamina-associated polypeptide (LAP) 2 family comprises up to six alternatively spliced
proteins in mammalian cells and three isoforms in Xenopus. LAP2β is a type II integral …