Calcium/calmodulin-dependent protein kinase II (CaMKII) is upregulated in diabetes and
significantly contributes to cardiac remodeling with increased risk of cardiac arrhythmias …

Ventricular arrhythmias and sudden cardiac death (SCD) occur most frequently in the setting
of coronary artery disease, cardiomyopathy and heart failure but are also increasingly …

Patients with cardiovascular disease and diabetes are at potentially higher risk of infection
and fatality due to COVID-19. Given the social and economic costs associated with disability …

Background Limited evidence is available on the associations of long-term exposure to
various fine particulate matter (PM 2.5) constituents with sub-clinical outcomes of …

Ventricular hypertrophy is a common pathological finding at autopsy that can act as a
substrate for arrhythmogenesis. Pathologists grapple with the significance of ventricular …

Hypertension affects an estimated 1.4 billion people and is a major cause of morbidity and
mortality worldwide. Early diagnosis and intervention can potentially decrease …

The introduction of sodium-glucose cotransporter 2 (SGLT2) inhibitors as a new and
effective class of therapeutic agents for type 2 diabetes (T2D) preventing the reabsorption of …

Obesity is global health problem with an estimated three billion people worldwide being
classified as overweight or obese. In addition to being associated with a range of adverse …

Obesity and sudden cardiac death (SCD) share common risk factors. Obesity, in and of itself,
can result in the development of SCD. Numerous epidemiologic and clinical studies have …

Transmural action potential duration differences and transmural conduction gradients aid
the synchronization of left ventricular repolarization, reducing vulnerability to transmural …