Rheumatoid arthritis: the old issue, the new therapeutic approach
M Babaahmadi, B Tayebi, NM Gholipour… - Stem Cell Research & …, 2023 - Springer
Rheumatoid arthritis (RA) is a chronic and systemic autoimmune disease of unknown
etiology. The most common form of this disease is chronic inflammatory arthritis, which …
etiology. The most common form of this disease is chronic inflammatory arthritis, which …
Comprehensive overview of microRNA function in rheumatoid arthritis
X Peng, Q Wang, W Li, G Ge, J Peng, Y Xu, H Yang… - Bone Research, 2023 - nature.com
MicroRNAs (miRNAs), a class of endogenous single-stranded short noncoding RNAs, have
emerged as vital epigenetic regulators of both pathological and physiological processes in …
emerged as vital epigenetic regulators of both pathological and physiological processes in …
Synovial fibroblasts as potential drug targets in rheumatoid arthritis, where do we stand and where shall we go?
Fibroblast-like synoviocytes or synovial fibroblasts (FLS) are important cellular components
of the inner layer of the joint capsule, referred to as the synovial membrane. They can be …
of the inner layer of the joint capsule, referred to as the synovial membrane. They can be …
Dual inhibition of glycolysis and glutaminolysis for synergistic therapy of rheumatoid arthritis
Background Synovial fibroblasts in rheumatoid arthritis (RAFLS) exhibit a pathological
aberration of glycolysis and glutaminolysis. Henceforth, we aimed to investigate if dual …
aberration of glycolysis and glutaminolysis. Henceforth, we aimed to investigate if dual …
Analysis and experimental validation of rheumatoid arthritis innate immunity gene CYFIP2 and pan-cancer
ZY Zhao, SJ He, XC Yu, XF Lai, S Tang… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a chronic, heterogeneous autoimmune disease. Its high
disability rate has a serious impact on society and individuals, but there is still a lack of …
disability rate has a serious impact on society and individuals, but there is still a lack of …
The synovial fluid fibroblast-like synoviocyte: A long-neglected piece in the puzzle of rheumatoid arthritis pathogenesis
DE Mahmoud, W Kaabachi, N Sassi… - Frontiers in …, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is a systemic autoimmune disease during which fibroblast-like
synoviocytes (FLS) contribute to both joint inflammation and destruction. FLS represent the …
synoviocytes (FLS) contribute to both joint inflammation and destruction. FLS represent the …
Epigenetic regulation in the pathogenesis of rheumatoid arthritis
Rheumatoid arthritis (RA) is an autoimmune disease. The etiology of RA remains
undetermined and the pathogenesis is complex. There remains a paucity of ideal …
undetermined and the pathogenesis is complex. There remains a paucity of ideal …
Therapeutic antibodies in medicine
P Sharma, RV Joshi, R Pritchard, K Xu, MA Eicher - Molecules, 2023 - mdpi.com
Antibody engineering has developed into a wide-reaching field, impacting a multitude of
industries, most notably healthcare and diagnostics. The seminal work on developing the …
industries, most notably healthcare and diagnostics. The seminal work on developing the …
Rheumatoid arthritis molecular targets and their importance to flavonoid‐based therapy
AT Rufino, M Freitas, C Proença… - Medicinal Research …, 2024 - Wiley Online Library
Rheumatoid arthritis (RA) is a progressive, chronic, autoimmune, inflammatory, and systemic
condition that primarily affects the synovial joints and adjacent tissues, including bone …
condition that primarily affects the synovial joints and adjacent tissues, including bone …
Cadherin signaling in cancer and autoimmune diseases
Cadherins mediate cell–cell adhesion through a dynamic process that is strongly dependent
on the cellular context and signaling. Cadherin regulation reflects the interplay between …
on the cellular context and signaling. Cadherin regulation reflects the interplay between …