Pathophysiology of atherosclerosis
S Jebari-Benslaiman, U Galicia-García… - International journal of …, 2022 - mdpi.com
Atherosclerosis is the main risk factor for cardiovascular disease (CVD), which is the leading
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …
cause of mortality worldwide. Atherosclerosis is initiated by endothelium activation and …
Calprotectin: from biomarker to biological function
The incidence of inflammatory bowel diseases (IBD) emerged with Westernisation of dietary
habits worldwide. Crohn's disease and ulcerative colitis are chronic debilitating conditions …
habits worldwide. Crohn's disease and ulcerative colitis are chronic debilitating conditions …
The emerging threat of (micro) thrombosis in COVID-19 and its therapeutic implications
JD McFadyen, H Stevens, K Peter - Circulation research, 2020 - Am Heart Assoc
The recent emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
and the ensuing global pandemic has presented a health emergency of unprecedented …
and the ensuing global pandemic has presented a health emergency of unprecedented …
Anti-angiogenic agents—overcoming tumour endothelial cell anergy and improving immunotherapy outcomes
ZR Huinen, EJM Huijbers, JR van Beijnum… - Nature Reviews …, 2021 - nature.com
Immune checkpoint inhibitors have revolutionized medical oncology, although currently only
a subset of patients has a response to such treatment. A compelling body of evidence …
a subset of patients has a response to such treatment. A compelling body of evidence …
DAMPs, PAMPs, and LAMPs in immunity and sterile inflammation
Recognizing the importance of leukocyte trafficking in inflammation led to some therapeutic
breakthroughs. However, many inflammatory pathologies remain without specific therapy …
breakthroughs. However, many inflammatory pathologies remain without specific therapy …
Neutrophils: New insights and open questions
Neutrophils are the first line of defense against bacteria and fungi and help combat parasites
and viruses. They are necessary for mammalian life, and their failure to recover after …
and viruses. They are necessary for mammalian life, and their failure to recover after …
[HTML][HTML] Bone metastases: an overview
F Macedo, K Ladeira, F Pinho, N Saraiva… - Oncology …, 2017 - ncbi.nlm.nih.gov
Bone is a frequent site of metastases and typically indicates a short-term prognosis in cancer
patients. Once cancer has spread to the bones it can rarely be cured, but often it can still be …
patients. Once cancer has spread to the bones it can rarely be cured, but often it can still be …
A history of exploring cancer in context
S Maman, IP Witz - Nature Reviews Cancer, 2018 - nature.com
The concept that progression of cancer is regulated by interactions of cancer cells with their
microenvironment was postulated by Stephen Paget over a century ago. Contemporary …
microenvironment was postulated by Stephen Paget over a century ago. Contemporary …