Jingmenviruses are a group of viruses identified recently, in 2014, and currently classified by
the International Committee on Taxonomy of Viruses as unclassified Flaviviridae. These …

In the last three decades, several flaviviruses of concern that belong to different antigenic
groups have expanded geographically. This has resulted in the presence of often more than …

The human monoclonal antibody C10 exhibits extraordinary cross-reactivity, potently
neutralizing Zika virus (ZIKV) and the four serotypes of dengue virus (DENV1–DENV4). Here …

Tick-borne encephalitis virus (TBEV) is a pathogenic, enveloped, positive-stranded RNA
virus in the family Flaviviridae. Structural studies of flavivirus virions have primarily focused …

The loss of detectable hepatitis B surface antigen (HBsAg) is considered a functional cure in
chronic hepatitis B. Naturally, HBsAg can be incorporated into the virion envelope or …

The flavivirus envelope glycoproteins prM and E drive the assembly of icosahedral, spiky
immature particles that bud across the membrane of the endoplasmic reticulum. Maturation …

Usutu virus (USUV) is an emerging arbovirus in Europe that has been increasingly identified
in asymptomatic humans and donated blood samples and is a cause of increased incidents …

We recently developed a chimeric flavivirus vaccine technology based on the novel insect-
specific Binjari virus (BinJV) and used this to generate a chimeric ZIKV vaccine (BinJ/ZIKA …

Vector-borne flaviviruses are responsible for nearly half a billion human infections
worldwide each year, resulting in millions of cases of debilitating and severe diseases and …

Maturation of dengue viruses (DENVs) alters the structure, immunity, and infectivity of the
virion and highly mature particles represent the dominant form in vivo. The production of …