Metals and alloys, including stainless steel, titanium and its alloys, cobalt alloys, and other
metals and alloys have been widely used clinically as implant materials, but implant-related …

Bone grafts have been predominated used to treat bone defects, delayed union or non-
union, and spinal fusion in orthopaedic clinically for a period of time, despite the emergency …

Copper is an indispensable trace metal element in the human body, which is mainly
absorbed in the stomach and small intestine and excreted into the bile. Copper is an …

Due to a prolonged life expectancy, the number of orthopedic-related fractures and
pathologies is increasing, leading to a tremendous demand for efficient orthopedic …

Copper is an essential trace element required for human life, and is involved in several
physiological mechanisms. Today researchers have found and confirmed that Cu has …

Backgroud Tissue engineering using cells, scaffolds, and bioactive molecules can promote
the repair and regeneration of injured tissues. Copper is an essential element for the human …

Abstract 3D printing technology is a new type of precision forming technology and the core
technology of the third industrial revolution. The powder-based 3D printing technology of …

Bone and joint-related infections remain the primary and most critical complications of
orthopedic surgery. We have innovatively prepared Zn-Cu alloys to achieve outstanding …

Macrophage has been gradually recognized as a central regulator in tissue regeneration,
and the study of how macrophage mediates biomaterials-induced bone regeneration …

Bone formation induced by divalent metal cations has been widely reported; however, the
underlying mechanism is unclear. Here we report that these cations stimulate skeleton …