Epidemiology of multiple sclerosis

J Howard, S Trevick, DS Younger - Neurologic clinics, 2016 - neurologic.theclinics.com
The Americas In 2007, Poser and Brinar 1 noted that published prevalence rates of multiple
sclerosis (MS) could be misleading with the reliance on clinical information and brain MRI …

Optic neuritis

AT Toosy, DF Mason, DH Miller - The Lancet Neurology, 2014 - thelancet.com
Acute optic neuritis is the most common optic neuropathy affecting young adults. Exciting
developments have occurred over the past decade in understanding of optic neuritis …

Safety and efficacy of rituximab in neuromyelitis optica spectrum disorders (RIN-1 study): a multicentre, randomised, double-blind, placebo-controlled trial

M Tahara, T Oeda, K Okada, T Kiriyama, K Ochi… - The Lancet …, 2020 - thelancet.com
Background Pharmacological prevention against relapses in patients with neuromyelitis
optica spectrum disorder (NMOSD) is developing rapidly. We aimed to investigate the safety …

Safety and efficacy of tocilizumab versus azathioprine in highly relapsing neuromyelitis optica spectrum disorder (TANGO): an open-label, multicentre, randomised …

C Zhang, M Zhang, W Qiu, H Ma, X Zhang… - The Lancet …, 2020 - thelancet.com
Background Azathioprine is used as a first-line treatment to prevent relapses of
neuromyelitis optica spectrum disorder (NMOSD). Tocilizumab has been reported to reduce …

Neuromyelitis optica: evaluation of 871 attacks and 1,153 treatment courses

I Kleiter, A Gahlen, N Borisow, K Fischer… - Annals of …, 2016 - Wiley Online Library
Objective Neuromyelitis optica (NMO) attacks often are severe, are difficult to treat, and
leave residual deficits. Here, we analyzed the frequency, sequence, and efficacy of …

[HTML][HTML] Update on the diagnosis and treatment of neuromyelitis optica: recommendations of the Neuromyelitis Optica Study Group (NEMOS)

C Trebst, S Jarius, A Berthele, F Paul, S Schippling… - Journal of …, 2014 - Springer
Neuromyelitis optica (NMO, Devic's syndrome), long considered a clinical variant of multiple
sclerosis, is now regarded as a distinct disease entity. Major progress has been made in the …

Overlapping demyelinating syndromes and anti–N‐methyl‐D‐aspartate receptor encephalitis

MJ Titulaer, R Höftberger, T Iizuka… - Annals of …, 2014 - Wiley Online Library
Objective To report the clinical, radiological, and immunological association of
demyelinating disorders with anti–N‐methyl‐D‐aspartate receptor (NMDAR) encephalitis …

Antibodies to MOG and AQP4 in adults with neuromyelitis optica and suspected limited forms of the disease

R Höftberger, M Sepulveda… - Multiple Sclerosis …, 2015 - journals.sagepub.com
Objective: We aimed to report the frequency and implications of antibodies to myelin
oligodendrocyte glycoprotein (MOG-ab) in adults with demyelinating syndromes suspicious …

[HTML][HTML] Evaluation of treatment response in adults with relapsing MOG-Ab-associated disease

A Cobo-Calvo, M Sepúlveda, F Rollot… - Journal of …, 2019 - Springer
Background Myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) are related to
several acquired demyelinating syndromes in adults, but the therapeutic approach is …

Treatment of MOG antibody associated disorders: results of an international survey

DH Whittam, V Karthikeayan, E Gibbons, R Kneen… - Journal of …, 2020 - Springer
Introduction While monophasic and relapsing forms of myelin oligodendrocyte glycoprotein
antibody associated disorders (MOGAD) are increasingly diagnosed world-wide, consensus …