▪ Abstract The past few years have seen exciting advances in understanding the structure
and function of catalytic RNA. Crystal structures of several ribozymes have provided detailed …

▪ Abstract Protocols to recover negative-strand RNA viruses entirely from cDNA have been
established in recent years, opening up this virus group to the detailed analysis of molecular …

The self-cleaving ribozyme of the hepatitis delta virus (HDV) is the only catalytic RNA known
to be required for the viability of a human pathogen. We obtained crystals of a 72-nucleotide …

A system has been established allowing the rescue of replicating measles viruses (MVs)
from cloned DNA. On one hand, plasmids were constructed from which MV antigenomic …

The addition of the hepatitis delta virus genomic ribozyme to the 3'end sequence of a Sendai
virus defective interfering RNA (DI-H4) allowed the reproducible and efficient replication of …

ACTIVATOR proteins bind to enhancer DNA elements and stimu-late the initiation of
transcription. It has been proposed1–3 that activators contact general initiation factors at a …

The genome of lymphocytic choriomeningitis virus (LCMV) consists of two negative-sense
single-stranded RNA segments, designated L and S. Both segments contain two viral genes …

HEPATITIS delta virus genomic and antigenomic RNAs contain a self-cleavage site
hypothesized to function in processing the viral RNA during replication1–3. Self-cleavage …

We have recovered infectious Sendai virus (SeV) from full‐length cDNA (FL‐3) by
transfecting this cDNA and pGEM plasmids expressing the nucleocapsid protein (NP) …

Hepatitis delta virus (HDV) is a small single‐straded RNA satellite of hepatitis B virus.
Although it is a human pathogen, it shares a number of features with a subset of the small …