Therapeutic strategies for COVID-19: progress and lessons learned
G Li, R Hilgenfeld, R Whitley, E De Clercq - Nature Reviews Drug …, 2023 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) pandemic has stimulated tremendous
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
efforts to develop therapeutic strategies that target severe acute respiratory syndrome …
COVID-19 convalescent plasma and clinical trials: understanding conflicting outcomes
D Focosi, M Franchini, L Pirofski… - Clinical microbiology …, 2022 - Am Soc Microbiol
Convalescent plasma (CP) recurs as a frontline treatment in epidemics because it is
available as soon as there are survivors. The COVID-19 pandemic represented the first …
available as soon as there are survivors. The COVID-19 pandemic represented the first …
An overview on the treatments and prevention against COVID-19
Y Panahi, AM Gorabi, S Talaei, F Beiraghdar… - Virology Journal, 2023 - Springer
Background The coronavirus disease 2019 (COVID-19) caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to plague the world. While …
respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to plague the world. While …
[HTML][HTML] Rates among hospitalized patients with COVID-19 treated with convalescent plasma: a systematic review and meta-analysis
Objective To examine the association of COVID-19 convalescent plasma transfusion with
mortality and the differences between subgroups in hospitalized patients with COVID-19 …
mortality and the differences between subgroups in hospitalized patients with COVID-19 …
Convalescent plasma therapy in COVID-19: Unravelling the data using the principles of antibody therapy
A Casadevall, MJ Joyner, LA Pirofski… - Expert review of …, 2023 - Taylor & Francis
Introduction When the COVID-19 pandemic struck no specific therapies were available and
many turned to COVID-19 convalescent plasma (CCP), a form of antibody therapy. The …
many turned to COVID-19 convalescent plasma (CCP), a form of antibody therapy. The …
Development and validation of a treatment benefit index to identify hospitalized patients with COVID-19 who may benefit from convalescent plasma
Importance Identifying which patients with COVID-19 are likely to benefit from COVID-19
convalescent plasma (CCP) treatment may have a large public health impact. Objective To …
convalescent plasma (CCP) treatment may have a large public health impact. Objective To …
A comprehensive review on the efficacy of several pharmacologic agents for the treatment of COVID-19
Simple Summary Treatments for coronavirus disease-2019 (COVID-19) have utilized a
variety of medications, including antivirals, immunomodulators, and other therapeutics such …
variety of medications, including antivirals, immunomodulators, and other therapeutics such …
The efficiency of convalescent plasma in COVID-19 patients: A systematic review and meta-analysis of randomized controlled clinical trials
Z Qian, Z Zhang, H Ma, S Shao, H Kang… - Frontiers in …, 2022 - frontiersin.org
The objective of this study was to assess whether convalescent plasma therapy could offer
survival advantages for patients with novel coronavirus disease 2019 (COVID-19). An …
survival advantages for patients with novel coronavirus disease 2019 (COVID-19). An …
Association between COVID-19 convalescent plasma antibody levels and COVID-19 outcomes stratified by clinical status at presentation
Background There is a need to understand the relationship between COVID-19
Convalescent Plasma (CCP) anti-SARS-CoV-2 IgG levels and clinical outcomes to optimize …
Convalescent Plasma (CCP) anti-SARS-CoV-2 IgG levels and clinical outcomes to optimize …
[HTML][HTML] Clinical research and drug regulation in the challenging times of individualized therapies: A pivotal role of Clinical Pharmacology
A Gómez-Outes, A Sancho-López, AJC Sansuan… - Pharmacological …, 2024 - Elsevier
Since the 1980s, medical specialists in Clinical Pharmacology have been playing a crucial
role in the development of drug regulation in Spain. In this article we report on the activities …
role in the development of drug regulation in Spain. In this article we report on the activities …