Lead, a systemic toxicant affecting virtually every organ system, primarily affects the central
nervous system, particularly the developing brain. Consequently, children are at a greater …

Lead (Pb) is considered a strong environmental toxin with human health repercussions. Due
to its widespread use and the number of people potentially exposed to different sources of …

Studies over the last decade demonstrate that adolescence is a brain maturation period from
childhood to adulthood. Plastic and dynamic processes drive adolescent brain development …

The effects of lead (Pb2+) on human health have been recognized since antiquity. However,
it was not until the 1970s that seminal epidemiological studies provided evidence on the …

Human exposure to neurotoxic metals is a global public health problem. Metals which cause
neurological toxicity, such as lead (Pb) and manganese (Mn), are of particular concern due …

Abstract Lead (Pb 2+) is a ubiquitous environmental neurotoxicant that continues to threaten
public health on a global scale. Epidemiological studies have demonstrated detrimental …

Lead is an important heavy metal used worldwide in several applications, especially in
industry. People exposed to lead can develop a wide range of symptoms associated with …

The NMDA receptor has been widely investigated in recent years as a target for the
pharmacological management of seizures, pain and a variety of neurological disorders. Its …

Long‐term deficits in cognitive function are the principal effects of lead (Pb2+) exposure in
children and can be modeled in experimental animals. Current therapeutic approaches in …

The detrimental effects of lead poisoning have been well known since ancient times, but
some of the most severe consequences of exposure to this metal have only been described …