Aggregation-induced emission (AIE), life and health

H Wang, Q Li, P Alam, H Bai, V Bhalla, MR Bryce… - ACS …, 2023 - ACS Publications
Light has profoundly impacted modern medicine and healthcare, with numerous
luminescent agents and imaging techniques currently being used to assess health and treat …

Recent strategies to develop innovative photosensitizers for enhanced photodynamic therapy

TC Pham, VN Nguyen, Y Choi, S Lee, J Yoon - Chemical reviews, 2021 - ACS Publications
This review presents a robust strategy to design photosensitizers (PSs) for various species.
Photodynamic therapy (PDT) is a photochemical-based treatment approach that involves the …

Copper doped carbon dots for addressing bacterial biofilm formation, wound infection, and tooth staining

M Liu, L Huang, X Xu, X Wei, X Yang, X Li, B Wang… - ACS …, 2022 - ACS Publications
Oral infectious diseases and tooth staining, the main challenges of dental healthcare, are
inextricably linked to microbial colonization and the formation of pathogenic biofilms …

Lighting up micro-/nanorobots with fluorescence

M Yang, X Guo, F Mou, J Guan - Chemical Reviews, 2022 - ACS Publications
Micro-/nanorobots (MNRs) can be autonomously propelled on demand in complex
biological environments and thus may bring revolutionary changes to biomedicines …

Noncancerous disease-targeting AIEgens

Y Duo, G Luo, W Zhang, R Wang, GG Xiao… - Chemical Society …, 2023 - pubs.rsc.org
Noncancerous diseases include a wide plethora of medical conditions beyond cancer and
are a major cause of mortality around the world. Despite progresses in clinical research …

Aggregation-induced emission nanoparticles for single near-infrared light-triggered photodynamic and photothermal antibacterial therapy

W Wang, F Wu, Q Zhang, N Zhou, M Zhang, T Zheng… - ACS …, 2022 - ACS Publications
Phototheranostics is a potential area for precision medicine, which has received increasing
attention for antibacterial applications. Integrating all phototheranostic modalities in a single …

Antimicrobial peptides towards clinical application: Delivery and formulation

C Wang, T Hong, P Cui, J Wang, J Xia - Advanced drug delivery reviews, 2021 - Elsevier
Antimicrobial peptides hold promise to supplement small molecules antibiotics and combat
the multidrug resistant microbes. There are however technical hurdles towards the clinical …

Neutrophil-like biomimic AIE nanoparticles with high-efficiency inflammatory cytokine targeting enable precise photothermal therapy and alleviation of inflammation

W Wang, Y Gao, M Zhang, Y Li, BZ Tang - ACS nano, 2023 - ACS Publications
Although photothermal therapy (PTT) has thrived as a promising treatment for drug-resistant
bacterial infections by avoiding the abuse of antibiotics, the remaining challenges that limit …

Photodynamic and photothermal co-driven CO-enhanced multi-mode synergistic antibacterial nanoplatform to effectively fight against biofilm infections

X Cai, J Tian, J Zhu, J Chen, L Li, C Yang… - Chemical Engineering …, 2021 - Elsevier
Photothermal therapy (PTT) and photodynamic therapy (PDT) have garnered much attention
for effectively treating biofilm infections. However, even highly efficient PTT reagents and …

The role of structural hydrophobicity on cationic amphiphilic aggregation-induced emission photosensitizer-bacterial interaction and photodynamic efficiency

MMS Lee, EY Yu, D Yan, JHC Chau, Q Wu, JWY Lam… - ACS …, 2023 - ACS Publications
The aggregation-induced emission photosensitizer (AIE PS) has stood out as an alternative
and competent candidate in bacterial theranostics, particularly with the use of cationic AIE …