Local staging of rectal cancer: the current role of MRI

C Klessen, P Rogalla, M Taupitz - European radiology, 2007 - Springer
With the advent of powerful gradient coil systems and high-resolution surface coils, magnetic
resonance imaging (MRI) has recently extended its role in the staging of rectal cancer. MRI …

Pathological complete response following pre-operative chemoradiotherapy in rectal cancer: analysis of phase II/III trials

A Hartley, KF Ho, C McConkey… - The British journal of …, 2005 - academic.oup.com
Pathological complete response (pCR) has been used as a marker for the efficacy of pre-
operative chemoradiotherapy (CRT) schedules in rectal cancer. To date there have been no …

Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data

M Maas, PJ Nelemans, V Valentini, P Das… - The lancet …, 2010 - thelancet.com
Background Locally advanced rectal cancer is usually treated with preoperative
chemoradiation. After chemoradiation and surgery, 15–27% of the patients have no residual …

Tumor regression grading after preoperative chemoradiotherapy for locally advanced rectal carcinoma revisited: updated results of the CAO/ARO/AIO-94 trial

E Fokas, T Liersch, R Fietkau… - Journal of Clinical …, 2014 - ascopubs.org
Purpose We previously described the prognostic impact of tumor regression grading (TRG)
on the outcome of patients with rectal carcinoma treated with preoperative …

Sphincter preservation following preoperative radiotherapy for rectal cancer: report of a randomised trial comparing short-term radiotherapy vs. conventionally …

K Bujko, MP Nowacki, A Nasierowska-Guttmejer… - Radiotherapy and …, 2004 - Elsevier
BACKGROUND AND PURPOSE: The aim was to verify whether preoperative conventionally
fractionated chemoradiation offers an advantage in sphincter preservation in comparison …

A phase II trial of neoadjuvant chemoradiation and local excision for T2N0 rectal cancer: preliminary results of the ACOSOG Z6041 trial

J Garcia-Aguilar, Q Shi, CR Thomas, E Chan… - Annals of surgical …, 2012 - Springer
Abstract Purpose We designed American College of Surgeons Oncology Group (ACOSOG)
Z6041, a prospective, multicenter, single-arm, phase II trial to assess the efficacy and safety …

The relationship of pathologic tumor regression grade (TRG) and outcomes after preoperative therapy in rectal cancer

FM Vecchio, V Valentini, BD Minsky… - International Journal of …, 2005 - Elsevier
Purpose: To examine the relationship between tumor regression grade (TRG) and outcomes
in patients with rectal cancer treated with preoperative therapy. Methods and Materials …

Complete pathologic response after combined modality treatment for rectal cancer and long-term survival: a meta-analysis

L Zorcolo, AS Rosman, A Restivo, M Pisano… - Annals of surgical …, 2012 - Springer
Background Complete pathologic response (CPR) after neoadjuvant chemoradiotherapy
(combined modality treatment, CMT) for rectal cancer seems associated with improved …

An interval> 7 weeks between neoadjuvant therapy and surgery improves pathologic complete response and disease–free survival in patients with locally advanced …

H Tulchinsky, E Shmueli, A Figer, JM Klausner… - Annals of surgical …, 2008 - Springer
Background We assessed whether the time interval between neoadjuvant therapy and
surgery affects the operative and postoperative morbidity and mortality, the pathologic …

Low rectal cancer: impact of radiation and chemotherapy on surgical treatment

A Habr-Gama, PMSB de Souza, U Ribeiro… - Diseases of the colon & …, 1998 - Springer
INTRODUCTION: The aim of this study was to evaluate the impact of combined radiotherapy
and chemotherapy (leucovorin and 5-fluorouracil) on the treatment of potentially resectable …