An understanding of the mechanisms whereby cell adhesion complexes (ACs) relay signals
bidirectionally across the plasma membrane is necessary to interpret the role of adhesion in …

Disabled-2 (DAB2), a key adaptor protein in clathrin mediated endocytosis, is implicated in
the regulation of key signalling pathways involved in homeostasis, cell positioning and …

Type IV secretion systems (T4SSs) are complex machines used by bacteria to deliver
protein and DNA complexes into target host cells,,,–. Conserved ATPases are essential for …

A long-standing paradigm in cell biology is the shutdown of endocytosis during mitosis.
There is consensus that transferrin uptake is inhibited after entry into prophase and that it …

The central nervous system (CNS) is a highly organised structure. Many signalling systems
work in concert to ensure that neural stem cells are appropriately directed to generate …

Clathrin-mediated endocytosis (CME) is the major internalisation route for many different
receptor types in mammalian cells. CME is shut down during early mitosis, but the …

Disabled‐2 (Dab2) is a multimodular scaffold protein with signaling roles in the domains of
cell growth, trafficking, differentiation, and homeostasis. Emerging evidences place Dab2 as …

Objective: Genome-wide studies showed that mutation in apoER2 (apolipoprotein E
receptor-2) is additive with ε4 polymorphism in the APOE gene on cardiovascular disease …

Endocytosis and mitosis are fundamental processes in a cell's life. Nearly 50 years of
research suggest that these processes are linked and that endocytosis is shut down as cells …

Abstract Disabled-2 (Dab2/DOC-2) is a mitogen-responsive adaptor protein required for
multiple cellular functions. It is involved in many signaling pathways and plays an integral …