Leveraging a translational research approach to drive diagnostic and treatment advances for autism
KJ Parker - Molecular psychiatry, 2022 - nature.com
Autism spectrum disorder (ASD) is a prevalent and poorly understood neurodevelopmental
disorder. There are currently no laboratory-based diagnostic tests to detect ASD, nor are …
disorder. There are currently no laboratory-based diagnostic tests to detect ASD, nor are …
[HTML][HTML] Rhesus macaque social functioning is paternally, but not maternally, inherited by sons: potential implications for autism
Background Quantitative autistic traits are common, heritable, and continuously distributed
across the general human population. Patterns of autistic traits within families suggest that …
across the general human population. Patterns of autistic traits within families suggest that …
[HTML][HTML] Tales from the life and lab of a female social neuroscientist
KJ Parker - Comprehensive Psychoneuroendocrinology, 2023 - Elsevier
This narrative review charts my unconventional path to becoming a social neuroscientist and
describes my research findings–some baffling, some serendipitous, some pivotal–in the field …
describes my research findings–some baffling, some serendipitous, some pivotal–in the field …
Vasopressin deficiency: a hypothesized driver of both social impairment and fluid imbalance in autism spectrum disorder
Scientific naming conventions are often idiosyncratic. For example, biological processes
have acquired names after a physician who described a syndrome (Alois Alzheimer), the …
have acquired names after a physician who described a syndrome (Alois Alzheimer), the …
[HTML][HTML] Naturally occurring low sociality in female rhesus monkeys: A tractable model for autism or not?
O Oztan, LA Del Rosso, SM Simmons, DKK Nguyen… - Molecular Autism, 2024 - Springer
Background Autism spectrum disorder (ASD) is characterized by persistent social interaction
impairments and is male-biased in prevalence. We have established naturally occurring low …
impairments and is male-biased in prevalence. We have established naturally occurring low …
Rhesus monkey sociality is stable across time and linked to variation in the initiation but not receipt of prosocial behavior
Rhesus monkeys and humans are highly social primates, yet both species exhibit
pronounced variation in social functioning, spanning a spectrum of sociality. Naturally …
pronounced variation in social functioning, spanning a spectrum of sociality. Naturally …
[HTML][HTML] Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome
SA Zlatic, D Duong, KKE Gadalla, B Murage, L Ping… - Iscience, 2022 - cell.com
MECP2 loss-of-function mutations cause Rett syndrome, a neurodevelopmental disorder
resulting from a disrupted brain transcriptome. How these transcriptional defects are …
resulting from a disrupted brain transcriptome. How these transcriptional defects are …
Oxymatrine Inhibits Malignant Behaviors of Breast Cancer Cells by Inhibiting miR-188 Expression to Up-Regulate Phosphatase and Tensin Homolog (PTEN)
X Wang, Y Hu, D Chen, L Cheng, L Yu… - Journal of Biomaterials …, 2023 - ingentaconnect.com
Oxymatrine has been applied to anti-cancer therapies for various cancers. The present study
aimed to investigate the potential impact of miR-188 on breast cancer (BC) cell progression …
aimed to investigate the potential impact of miR-188 on breast cancer (BC) cell progression …