Design, Synthesis, Antimicrobial Properties, and Molecular Docking of Novel Furan-Derived Chalcones and Their 3,5-Diaryl-∆2-pyrazoline Derivatives

IS Mahdi, AM Abdula, AMN Jassim, Y Baqi - Antibiotics, 2023 - mdpi.com
The present work focuses on the synthesis and preliminary structure activity relationships
(SARs) of furan-derived chalcones and their corresponding∆ 2-pyrazoline derivatives as …

[PDF][PDF] Synthesis, characterization, preliminary molecular docking, pharmacological activity, and ADME studies of some new pyrazoline derivatives as anti-breast …

HR Fadhil, AMR Raauf, MF Mahdi - Pharmacia, 2024 - pharmacia.pensoft.net
This work studied the anti-breast cancer activities of pyrazoline-containing
benzenesulfonamides (6–10) in vitro and silico. The GOLD suite performed molecular …

[PDF][PDF] Synthesis, characterization, molecular docking, in silico ADME study, and in vitro cytotoxicity evaluation of new pyridine derivatives of nabumetone

BK Jameel, AMR Raauf, WAK Abbas - Al Mustansiriyah Journal of …, 2023 - iasj.net
New pyridine derivatives of nabumetone containing 2-amino 3-cyano moieties were
synthesized and aimed to introduce new EGFR kinase inhibitors through two methods either …

Synthesis, Characterization, Anti-Inflammatory, and Antimicrobial Evaluation of New 2-Pyrazolines Derivatives Derived from Guaiacol

TNA Omar - Iraqi Journal of Pharmaceutical Sciences (P …, 2023 - bijps.uobaghdad.edu.iq
Chalcones were used to synthesis series of 2-pyrazoline derivatives and evaluated their
antimicrobial and anti-inflammatory activities (E)-1, 3-diphenylprop-2-en-1-one (1-5) were …

The Use of the Carbonyl Group (C-3) of Isatin for the Construction of Pyrazoline Moiety and the Study of its Antioxidant Activity

RS Dawood, FN Faisal - Iraqi Journal of Science, 2024 - ijs.uobaghdad.edu.iq
A series of novel pyrazoline derivatives 5-13 were synthesized in three steps from isatin,
with yields ranging from 40 to 72% over the multistep procedure. The first step included the …

Synthesis and Preliminary Anti-Inflammatory and Anti-Microbial Evaluation of New 4, 5-Dihydro-1H-Pyrazole Derivatives

S Kanaan, TNA Omar - … Sciences (P-ISSN 1683-3597 E …, 2023 - bijps.uobaghdad.edu.iq
Organic compounds with pyrazole cores have a variety of uses, notably in the
pharmaceutical and agrochemical sectors. The interest in creating pyrazole compounds …

[PDF][PDF] α-Functionalization of the Carbonyl Group for the Construction of Pyrazoline Rings Derived from 1, 3-Indandione

RT Ali, RS Dawood - Iraqi Journal of Science, 2024 - iasj.net
This work includes the synthesis of new pyrazoline derivatives 5-13 over three steps starting
from 1, 3-indandione. The first step included the acylation of 1, 3-indandione with acetyl …

Synthesis, identification and evaluation of molecular docking and experimental anti-cancer and antioxidant activity of new spiro four membered ring derivatives …

HAM Rasheed, SMH Al-Majidi - Natural Product Research, 2024 - Taylor & Francis
Abstract Spiro-5-nitro isatino aza-β-lactams were produced by a [2+ 2] cycloaddition of 5-
nitro isatin Schiff bases [1–5] with different aromatic isocyanate and thioisocyanate. 1HNMR …

[PDF][PDF] Synthesis, Identification, and Biological Activity Investigation of New Pyrazolines Derived from Vanillin

RT Ali, RS Dawood - Iraqi Journal of Science, 2024 - iasj.net
This work includes the synthesis of new pyrazoline derivatives 6-20 over two steps. The first
step included a condensation between vanillin and various aromatic ketones …