A substantial portion of the genomes of most multicellular eukaryotes consists of large arrays
of tandemly repeated sequence, collectively called satellite DNA. The processes generating …

Repetitive elements (REs), such as transposable elements (TEs) and satellites, comprise
much of the genome. Here, we review how TEs and (peri) centromeric satellite DNA may …

Centromeres are essential chromosomal regions that mediate kinetochore assembly and
spindle attachments during cell division. Despite their functional conservation, centromeres …

Heterochromatic repeat-rich regions are often missing from even the best genome
assemblies. Chang and Larracuente designed a de novo assembly strategy to improve the …

A universal and unquestioned characteristic of eukaryotic cells is that the genome is divided
into multiple chromosomes and encapsulated in a single nucleus. However, the underlying …

The rapid evolution of repetitive DNA sequences, including satellite DNA, tandem
duplications, and transposable elements, underlies phenotypic evolution and contributes to …

Simple non-coding tandem repeats known as satellite DNA are observed widely across
eukaryotes. These repeats occupy vast regions at the centromere and pericentromere of …

The classical human satellite DNAs, also referred to as human satellites 1, 2 and 3 (HSat1,
HSat2, HSat3, or collectively HSat1–3), occur on most human chromosomes as large …

The eukaryotic genome is packaged into transcriptionally active euchromatin and silent
heterochromatin, with most studies focused on the former encompassing the majority of …

Centromeres are the basic unit for chromosome inheritance, but their evolutionary dynamics
is poorly understood. We generate high-quality reference genomes for multiple Drosophila …