Sirtuins as Potential Targets for Neuroprotection: Mechanisms of Early Brain Injury Induced by Subarachnoid Hemorrhage
K Lei, R Wu, J Wang, X Lei, E Zhou, R Fan… - Translational Stroke …, 2023 - Springer
Subarachnoid hemorrhage (SAH) is a prevalent cerebrovascular disease with significant
global mortality and morbidity rates. Despite advancements in pharmacological and surgical …
global mortality and morbidity rates. Despite advancements in pharmacological and surgical …
Salvianolic acid B ameliorates neuroinflammation and neuronal injury via blocking NLRP3 inflammasome and promoting SIRT1 in experimental subarachnoid …
D Xia, J Yuan, D Wu, H Dai, Z Zhuang - Frontiers in Immunology, 2023 - frontiersin.org
The nucleotide-binding oligomerization domain (NOD)-like receptor family pyrin domain
containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a …
containing 3 (NLRP3) inflammasome-mediated immuno-inflammatory response plays a …
Therapeutic potential of natural compounds in subarachnoid haemorrhage
J Tan, H Zhu, Y Zeng, J Li, Y Zhao, M Li - Neuroscience, 2024 - Elsevier
Subarachnoid hemorrhage (SAH) is a common and fatal cerebrovascular disease with high
morbidity, mortality and very poor prognosis worldwide. SAH can induce a complex series of …
morbidity, mortality and very poor prognosis worldwide. SAH can induce a complex series of …
Controlling the familywise error rate in widefield optical neuroimaging of functional connectivity in mice
BR White, C Chan, T Adepoju, RT Shinohara… - …, 2023 - spiedigitallibrary.org
Significance Statistical inference in functional neuroimaging is complicated by the multiple
testing problem and spatial autocorrelation. Common methods in functional magnetic …
testing problem and spatial autocorrelation. Common methods in functional magnetic …
Conditioning-based therapeutics for aneurysmal subarachnoid hemorrhage–A critical review
S Pugazenthi, AJ Norris, DC Lauzier… - Journal of Cerebral …, 2024 - journals.sagepub.com
Aneurysmal subarachnoid hemorrhage (SAH) carries significant mortality and morbidity,
with nearly half of SAH survivors having major cognitive dysfunction that impairs their …
with nearly half of SAH survivors having major cognitive dysfunction that impairs their …
Sirt1 activation promotes long-term functional recovery after subarachnoid hemorrhage in rats
Background An increase in sirtuin 1 (SIRT1) reportedly attenuates early brain injury, delayed
cerebral ischemia, and short-term neurologic deficits in rodent models of subarachnoid …
cerebral ischemia, and short-term neurologic deficits in rodent models of subarachnoid …
[HTML][HTML] Semaglutide alleviates early brain injury following subarachnoid hemorrhage by suppressing ferroptosis and neuroinflammation via SIRT1 pathway
L Chen, H Xu, C Zhang, J He… - American Journal of …, 2024 - ncbi.nlm.nih.gov
Objectives: Subarachnoid hemorrhage (SAH) is a major cause of incapacity and death,
imposing a significant economic burden globally. Additionally, SAH is the third most …
imposing a significant economic burden globally. Additionally, SAH is the third most …
NAD-Dependent Protein Deacetylase Sirtuin-1 Mediated Mitophagy Regulates Early Brain Injury After Subarachnoid Hemorrhage
G Wang, N Lin - Journal of Inflammation Research, 2024 - Taylor & Francis
Background This study focuses on the role of SIRT1 in neuroinflammation caused by early
brain injury (EBI) after subarachnoid hemorrhage (SAH), and explores its mechanism in …
brain injury (EBI) after subarachnoid hemorrhage (SAH), and explores its mechanism in …
Efficacy of resveratrol in experimental subarachnoid hemorrhage animal models: a stratified meta-analysis
J Tan, R Song, S Luo, W Fu, Y Ma, L Zheng… - Frontiers in …, 2022 - frontiersin.org
Background: Subarachnoid hemorrhage (SAH) is a serious neurosurgical emergency with
extremely high morbidity and mortality rates. Resveratrol (RES), a natural polyphenolic …
extremely high morbidity and mortality rates. Resveratrol (RES), a natural polyphenolic …
Pterostilbene Attenuates Subarachnoid Hemorrhage‐Induced Brain Injury through the SIRT1‐Dependent Nrf2 Signaling Pathway
Z Zhang, J Fang, J Zhou, F Ding, G Zhou… - Oxidative medicine …, 2022 - Wiley Online Library
Neuroinflammatory injury, oxidative insults, and neuronal apoptosis are major causes of
poor outcomes after subarachnoid hemorrhage (SAH). Pterostilbene (PTE), an analog of …
poor outcomes after subarachnoid hemorrhage (SAH). Pterostilbene (PTE), an analog of …