Chemistry and biology of non-tetramic γ-hydroxy-γ-lactams and γ-alkylidene-γ-lactams from natural sources

B Nay, N Riache, L Evanno - Natural Product Reports, 2009 - pubs.rsc.org
Covering: from 1960 to 2008 Natural products containing non-tetramic γ-hydroxy-γ-lactams
and γ-alkylidene-γ-lactams are usually but not exclusively derived from the mixed polyketide …

Fusarin C Biosynthesis in Fusarium moniliforme and Fusarium venenatum

Z Song, RJ Cox, CM Lazarus, TJ Simpson - ChemBioChem, 2004 - Wiley Online Library
Fragments of polyketide synthase (PKS) genes were amplified from complementary DNA
(cDNA) of the fusarin C producing filamentous fungi Fusarium moniliforme and Fusarium …

Domino syntheses of bioactive tetronic and tetramic acids

R Schobert - Naturwissenschaften, 2007 - Springer
Natural products containing tetronic acid or tetramic acid moieties continue to attract the
interest of chemists, biologists, and physicians due to their challenging structures and to the …

Biosynthesis of the 2‐Pyridone Tenellin in the Insect Pathogenic Fungus Beauveria bassiana

KL Eley, LM Halo, Z Song, H Powles, RJ Cox… - …, 2007 - Wiley Online Library
Genomic DNA from the insect pathogenic fungus Beauveria bassiana was used as a
template in a PCR with degenerate primers designed to amplify a fragment of a C‐methyl …

Induction of New Lactam Derivatives From the Endophytic Fungus Aplosporella javeedii Through an OSMAC Approach

Y Gao, F Stuhldreier, L Schmitt, S Wesselborg… - Frontiers in …, 2020 - frontiersin.org
Fermentation of the endophytic fungus Aplosporella javeedii on solid rice medium in
presence of either 3.5% NaNO3 or 3.5% monosodium glutamate caused a significant …

Virgaricins C and D, new pramanicin analogs produced by Apiospora sp. FKI-8058

S Kimura, Y Watanabe, Y Mikasa, R Miyano… - The Journal of …, 2024 - nature.com
Two new pramanicin analogs, named virgaricins C (1) and D (2), were discovered by
physicochemical screening from a static cultured material of Apiospora sp. FKI-8058. Their …

Biosynthetic studies on the antibiotics PF1140: a novel pathway for a 2-pyridone framework

Y Fujita, H Oguri, H Oikawa - Tetrahedron letters, 2005 - Elsevier
Incorporation of labeled acetate and l-serine into PF1140 in Eupenicillium sp. indicated that
the skeleton of PF1140 is derived from five acetates and a l-serine. Upon administration of …

Antimicrobial Metabolites against Methicillin-Resistant Staphylococcus aureus from the Endophytic Fungus Neofusicoccum australe

MM Cadelis, S Geese, BB Uy, DR Mulholland… - Molecules, 2021 - mdpi.com
Antimicrobial bioassay-guided fractionation of the endophytic fungi Neofusicoccum australe
led to the isolation of a new unsymmetrical naphthoquinone dimer, neofusnaphthoquinone …

Phosphorus ylide based functionalizations of tetronic and tetramic acids

R Schobert, M Dietrich, G Mullen… - Synthesis, 2006 - thieme-connect.com
The versatility of the ylide (triphenylphosphoranylidene) ketene (Ph 3 P= C= C= O, 3) in the
construction of tetronic and tetramic acids from various carboxylic acid derivatives is …

Synthesis of mimics of pramanicin from pyroglutamic acid and their antibacterial activity

SWB Tan, CLL Chai, MG Moloney… - The Journal of Organic …, 2015 - ACS Publications
Epoxypyrrolidinones are available by epoxidation of carboxamide-activated bicyclic lactam
substrates derived from pyroglutamate using aqueous hydrogen peroxide and tertiary amine …