Toxoplasmosis: Current and emerging parasite druggable targets
RE Hajj, L Tawk, S Itani, M Hamie, J Ezzeddine… - Microorganisms, 2021 - mdpi.com
Toxoplasmosis is a prevalent disease affecting a wide range of hosts including
approximately one-third of the human population. It is caused by the sporozoan parasite …
approximately one-third of the human population. It is caused by the sporozoan parasite …
Human cyclosporiasis
A Giangaspero, RB Gasser - The Lancet Infectious Diseases, 2019 - thelancet.com
Cyclospora species are socioeconomically important protistan pathogens. Cyclospora
cayetanensis is usually transmitted via food or water to a human host via the faecal–oral …
cayetanensis is usually transmitted via food or water to a human host via the faecal–oral …
Toxoplasma gondii infection: novel emerging therapeutic targets
J Müller, A Hemphill - Expert opinion on therapeutic targets, 2023 - Taylor & Francis
Introduction Toxoplasmosis constitutes a challenge for public health, animal production, and
welfare. So far, only a limited panel of drugs has been marketed for clinical applications. In …
welfare. So far, only a limited panel of drugs has been marketed for clinical applications. In …
Identification of putative drug targets in Vancomycin-resistant Staphylococcus aureus (VRSA) using computer aided protein data analysis
Vancomycin-resistant Staphylococcus aureus (VRSA) is a Gram-positive, facultative aerobic
bacterium which is evolved from the extensive exposure of Vancomycin to Methicillin …
bacterium which is evolved from the extensive exposure of Vancomycin to Methicillin …
Genetic similarities between Cyclospora cayetanensis and cecum-infecting avian Eimeria spp. in apicoplast and mitochondrial genomes
K Tang, Y Guo, L Zhang, LA Rowe, DM Roellig… - Parasites & …, 2015 - Springer
Background Cyclospora cayetanensis is an important cause for diarrhea in children in
developing countries and foodborne outbreaks of cyclosporiasis in industrialized nations. To …
developing countries and foodborne outbreaks of cyclosporiasis in industrialized nations. To …
Therapy for ocular toxoplasmosis–the future
JG Garweg, MR Stanford - Ocular immunology and inflammation, 2013 - Taylor & Francis
Background: Treatment of ocular toxoplasmosis is aimed at stabilizing visual function and
reducing recurrence rates. Methods: Small controlled studies indicate that available …
reducing recurrence rates. Methods: Small controlled studies indicate that available …
Disorganized muscle protein-1 (DIM-1) of filarial parasite Brugia malayi: cDNA cloning, expression, purification, structural modeling and its potential as vaccine …
We have recently identified disorganized muscle protein-1 (DIM-1) in one of the
proinflammatory fractions of the human filaria Brugia malayi adult worm. The present study …
proinflammatory fractions of the human filaria Brugia malayi adult worm. The present study …
Bioinformatics of excretory/secretory proteins of Toxoplasma gondii strain ME49
Z Ma, AMM Alhameed, AC Kaminga, B Lu, X Li… - Microbial …, 2020 - Elsevier
Toxoplasma gondii is an obligate intracellular parasite that is globally distributed and can
infect almost all warm-blooded animals, including humans. While vaccines are not available …
infect almost all warm-blooded animals, including humans. While vaccines are not available …
Predictions of enzymatic parameters: a mini-review with focus on enzymes for biofuel
S Yan, G Wu - Applied biochemistry and biotechnology, 2013 - Springer
Enzymatic reactions are very basic processes in biological systems, and parameters related
to enzymatic reactions always provide good indicators for understanding of mechanisms …
to enzymatic reactions always provide good indicators for understanding of mechanisms …
Therapeutic Targets on Toxoplasma gondii parasite in combatting Toxoplasmosis
The status of toxoplasmosis management is challenged by drug intolerance, compromised
efficacy and potential development of drug resistance. However, currently, there are very …
efficacy and potential development of drug resistance. However, currently, there are very …