Recent advances in organ chip (or,“organ-on-a-chip”) technologies and microphysiological
systems (MPS) have enabled in vitro investigation of endothelial cell function in biomimetic …

These models represent many different types of tissue and disease states. Some devices
have relatively simple geometry and few cell types, while others use complex …

Per-and poly-fluoroalkyl substances (PFAS) are emerging contaminants of concern because
of their wide use, persistence, and potential to be hazardous to both humans and the …

The vascular tree is crucial for the survival and function of large living tissues. Despite
breakthroughs in 3D bioprinting to endow engineered tissues with large blood vessels, there …

While tumor organoids have revolutionized cancer research by recapitulating the cellular
architecture and behaviors of real tumors in vitro, their lack of functional vasculature hinders …

Nanosized drug formulations are broadly explored for the improvement of cancer therapy.
Prediction of in vivo nanoparticle (NP) behavior, however, is challenging, given the …

Tissue engineering and regenerative medicine have made great progress in recent
decades, as the fields of bioengineering, materials science, and stem cell biology have …

Vascularized organoid-on-a-chip (VOoC) models achieve substance exchange in deep
layers of organoids and provide a more physiologically relevant system in vitro. Common …

Vascular pathologies are prevalent in a broad spectrum of diseases, necessitating a deeper
understanding of vascular biology, particularly in overcoming the oxygen and nutrient …

Xenohormesis proposes that phytochemicals produced to combat stressors in the host plant
exert biochemical effects in animal cells lacking cognate receptors. Xenohormetic …