Sry: the master switch in mammalian sex determination
K Kashimada, P Koopman - Development, 2010 - journals.biologists.com
SRY, the mammalian Y-chromosomal testis-determining gene, induces male sex
determination. Recent studies in mice reveal that the major role of SRY is to achieve …
determination. Recent studies in mice reveal that the major role of SRY is to achieve …
One tissue, two fates: molecular genetic events that underlie testis versus ovary development
J Brennan, B Capel - Nature Reviews Genetics, 2004 - nature.com
The pivotal point of vertebrate sex determination is the development of the gonad into a
testis or ovary, which governs phenotypic sex through the production of hormones. The …
testis or ovary, which governs phenotypic sex through the production of hormones. The …
[图书][B] Hormones and animal social behavior
E Adkins-Regan - 2013 - degruyter.com
Research into the lives of animals in their natural environments has revealed a rich tapestry
of complex social relationships and previously unsuspected social and mating systems. The …
of complex social relationships and previously unsuspected social and mating systems. The …
The KiSS-1 receptor GPR54 is essential for the development of the murine reproductive system
S Funes, JA Hedrick, G Vassileva, L Markowitz… - Biochemical and …, 2003 - Elsevier
GPR54 is a G-protein-coupled receptor that displays a high percentage of identity in the
transmembrane domains with the galanin receptors. The ligand for GPR54 has been …
transmembrane domains with the galanin receptors. The ligand for GPR54 has been …
Plasticity of gene‐regulatory networks controlling sex determination: of masters, slaves, usual suspects, newcomers, and usurpators
Sexual dimorphism is one of the most pervasive and diverse features of animal morphology,
physiology, and behavior. Despite the generality of the phenomenon itself, the mechanisms …
physiology, and behavior. Despite the generality of the phenomenon itself, the mechanisms …
[图书][B] Making sex revisited: Dekonstruktion des Geschlechts aus biologisch-medizinischer Perspektive
HJ Voß - 2015 - library.oapen.org
Die fortgesetzte Suche nach dem einzelnen ‚geschlechtsdeterminierenden Gen ': SRY als
TDF? 250 Downstream von SRY–weitere Gene, die hierarchisch unterhalb von SRY als an …
TDF? 250 Downstream von SRY–weitere Gene, die hierarchisch unterhalb von SRY als an …
Identification of SOX3 as an XX male sex reversal gene in mice and humans
Sex in mammals is genetically determined and is defined at the cellular level by sex
chromosome complement (XY males and XX females). The Y chromosome–linked gene sex …
chromosome complement (XY males and XX females). The Y chromosome–linked gene sex …
Sex determination and SRY: down to a wink and a nudge?
R Sekido, R Lovell-Badge - Trends in Genetics, 2009 - cell.com
Sex-determining region Y (Sry) is the crucial gene that initiates male sex determination in
most mammals. Although several components of the pathway regulating sexual …
most mammals. Although several components of the pathway regulating sexual …
[HTML][HTML] SOX9 is up-regulated by the transient expression of SRY specifically in Sertoli cell precursors
The Y chromosome gene Sry encodes a transcription factor required to initiate testis
development. The related autosomal gene Sox9 is up-regulated shortly after the onset of Sry …
development. The related autosomal gene Sox9 is up-regulated shortly after the onset of Sry …
The molecular action and regulation of the testis-determining factors, SRY (sex-determining region on the Y chromosome) and SOX9 [SRY-related high-mobility group …
VR Harley, MJ Clarkson, A Argentaro - Endocrine reviews, 2003 - academic.oup.com
Despite 12 yr since the discovery of SRY, little is known at the molecular level about how
SRY and the SRY-related protein, SOX9 [SRY-related high-mobility group (HMG) box 9] …
SRY and the SRY-related protein, SOX9 [SRY-related high-mobility group (HMG) box 9] …