Chalcones (1, 3-diaryl-2-propen-1-ones) are precursors for flavonoids and isoflavonoids,
which are common simple chemical scaffolds found in many naturally occurring compounds …

Abstract Chalcone or (E)-1, 3-diphenyl-2-propene-1-one scaffold remained a fascination
among researchers in the 21st century due to its simple chemistry, ease of synthesis and a …

The continuous emergency of drug‐resistant cancers and the low specificity of anticancer
agents have been the major challenges in the control and treatment of cancer, making an …

The emergence of drug-resistance and the low specificity of anticancer agents are the major
challenges in the treatment of cancer and can result in many side effects, creating an urgent …

Malaria is a vector-and blood-borne infection that is responsible for a large number of
deaths around the world. Most of the currently used antimalarial therapeutics suffer from …

Background Malaria extensively leads to mortality and morbidity in endemic regions, and the
emergence of drug resistant parasites is alarming. Plant derived synthetic pharmaceutical …

ABSTRACT According to the World Health Organization, malaria remains one of the biggest
public health problems in the world. The development of resistance is a current concern …

Malaria, one of the most striking, re‐emerging infectious diseases caused by the genus
Plasmodium, places a huge burden on global healthcare systems. A major challenge in the …

A novel series of pyrazolyl chalcones containing quinoline scaffold, 5 av has been
synthesized by Claisen Schimdt condensation of aromatic acetophenone with 1-(4 …

In an attempt to find potential anticancer agents, a series of novel ethyl 4-(3-(aryl)-1-phenyl-
1H-pyrazol-4-yl)-2-oxo-6-(pyridin-3-yl) cyclohex-3-enecarboxylates 5a-i and 5-(3-(4 …