α-Arrestins, also called arrestin-related trafficking adaptors (ARTs), constitute a large family
of proteins conserved from yeast to humans. Despite their evolutionary precedence over …

Plasma membrane transporters play pivotal roles in the import of nutrients, including sugars,
amino acids, nucleobases, carboxylic acids, and metal ions, that surround fungal cells. The …

G-protein-coupled receptors (GPCRs) are integral membrane proteins that initiate
responses to extracellular stimuli by mediating ligand-dependent activation of cognate …

Monoterpenoids, such as the plant metabolite geraniol, are of high industrial relevance
since they are important fragrance materials for perfumes, cosmetics, and household …

Targeted endocytosis of plasma membrane (PM) proteins allows cells to adjust their
complement of membrane proteins to changing extracellular conditions. For a wide variety of …

Proper regulation of plasma membrane protein endocytosis by external stimuli is required
for cell growth and survival. In yeast, excess levels of certain nutrients induce endocytosis of …

In yeast, the main ubiquitin ligase responsible for the sorting of proteins to the lysosomal
vacuole is Rsp5, a member of the Nedd4 family of ligases whose distinguishing features are …

In response to changes in nutrient conditions, cells rearrange the composition of plasma
membrane (PM) transporters to optimize their metabolic flux. Not only transcriptional gene …

Endocytosis of membrane proteins in yeast requires α-arrestin-mediated ubiquitylation by
the ubiquitin ligase Rsp5. Yet, the diversity of α-arrestin targets studied is restricted to a …

Simple Summary Preserving the integrity of protein biosynthesis involves maintaining a
delicate equilibrium between translation accuracy and speed. In the current study we …