COVID‐19 as a blood clotting disorder masquerading as a respiratory illness: a cerebrovascular perspective and therapeutic implications for stroke thrombectomy

V Janardhan, V Janardhan… - Journal of …, 2020 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) as the name suggests
was initially thought to only cause a respiratory illness. However, several reports have been …

Potential mechanisms of cerebrovascular diseases in COVID-19 patients

M Lou, D Yuan, S Liao, L Tong, J Li - Journal of NeuroVirology, 2021 - Springer
Since the outbreak of coronavirus disease 2019 (COVID-19) in 2019, it is gaining worldwide
attention at the moment. Apart from respiratory manifestations, neurological dysfunction in …

The weight of IgA anti-β2glycoprotein I in the antiphospholipid syndrome pathogenesis: closing the gap of seronegative antiphospholipid syndrome

O Cabrera-Marante, E Rodríguez de Frías… - International Journal of …, 2020 - mdpi.com
The specific value of IgA Anti-β2glycoprotein I antibodies (aB2GP1) in the diagnosis and
management of antiphospholipid syndrome (APS) is still controversial and a matter of active …

[HTML][HTML] Pathophysiology of antiphospholipid syndrome

D Green - Thrombosis and Haemostasis, 2022 - thieme-connect.com
The antiphospholipid syndrome is characterized by antibodies directed against
phospholipid-binding proteins and phospholipids attached to cell membrane receptors …

Arterial thrombosis in antiphospholipid syndrome (APS): Clinical approach and treatment. A systematic review

C Cheng, GY Cheng, G Denas, V Pengo - Blood Reviews, 2021 - Elsevier
Abstract Thrombotic Antiphospholipid Syndrome (APS) is a condition affecting young
individuals in whom a thromboembolic event occurs in the presence of circulating …

Antiphospholipid syndrome: state of the art of clinical management

L Depietri, MR Veropalumbo, MC Leone… - … Drugs and Therapy, 2023 - Springer
Antiphospholipid syndrome (APS) is a systemic autoimmune disorder clinically
characterized by recurrent arterial and venous thrombosis and/or pregnancy morbidity in the …

Managing antiphospholipid syndrome in children and adolescents: current and future prospects

AG Islabao, VC Trindade, LMH da Mota, DCO Andrade… - Pediatric Drugs, 2022 - Springer
Pediatric antiphospholipid syndrome (APS) is a rare acquired multisystem autoimmune
thromboinflammatory condition characterized by thrombotic and non-thrombotic clinical …

Lysine residues control the conformational dynamics of beta 2-glycoprotein I

I Buchholz, P Nestler, S Köppen… - Physical Chemistry …, 2018 - pubs.rsc.org
One of the major problems in the study of the dynamics of proteins is the visualization of
changing conformations that are important for processes ranging from enzyme catalysis to …

The IgA isotype of anti-β2 glycoprotein I antibodies recognizes epitopes in domains 3, 4, and 5 that are located in a lateral zone of the molecule (L-Shaped)

M Serrano, JA Martinez-Flores, GL Norman… - Frontiers in …, 2019 - frontiersin.org
Background: Antiphospholipid syndrome (APS) is characterized by thrombosis and/or
pregnancy morbidity with presence of anti-phospholipid antibodies (aPL). The APS …

Endothelial dysfunction and COVID‑19

J Daher - Biomedical Reports, 2021 - spandidos-publications.com
It is hypothesized that several comorbidities increase the severity of COVID‑19 symptoms.
Cardiovascular disease including hypertension was shown to play a critical role in the …