Brucein D augments the chemosensitivity of gemcitabine in pancreatic cancer via inhibiting...

J Zhang, HX Xu, JQ Zhu, YX Dou… - International Journal of …, 2023 - ncbi.nlm.nih.gov

Nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor that regulates redox
homeostasis, plays a pivotal role in several cellular processes such as cell proliferation and …

被引用次数：16 相关文章所有 7 个版本

[PDF] frontiersin.org

Nrf2 signaling pathway: current status and potential therapeutic targetable role in human cancers

L Lin, Q Wu, F Lu, J Lei, Y Zhou, Y Liu, N Zhu… - Frontiers in …, 2023 - frontiersin.org

Cancer is a borderless global health challenge that continues to threaten human health.
Studies have found that oxidative stress (OS) is often associated with the etiology of many …

被引用次数：8 相关文章所有 5 个版本

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[HTML][HTML] Circ_0006790 carried by bone marrow mesenchymal stem cell-derived exosomes regulates S100A11 DNA methylation through binding to CBX7 in …

G Gao, L Wang, C Li - American Journal of Cancer Research, 2022 - ncbi.nlm.nih.gov

Extracellular vesicles, particularly exosomes, play a vital role via their cargoes. Their
potential in pancreatic ductal adenocarcinoma (PDAC), one of the leading causes of cancer …

被引用次数：16 相关文章所有 3 个版本

STAT3 inhibition enhances gemcitabine sensitivity in pancreatic cancer by suppressing EMT, immune escape and inducing oxidative stress damage

H Guo, Z Hu, X Yang, Z Yuan, Y Gao, J Chen… - International …, 2023 - Elsevier

Pancreatic cancer (PC) is a highly-malignant tumor of the digestive system with a very poor
prognosis and high mortality. Chemotherapy and PD-1/PD-L1 immune checkpoint blockade …

被引用次数：4 相关文章所有 3 个版本

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Brucein D imparts a growth inhibitory effect in multiple myeloma cells by abrogating the Akt‐driven signaling pathway

YY Jung, CD Mohan, S Rangappa, JY Um… - IUBMB …, 2023 - Wiley Online Library

The Akt signaling pathway is an oncogenic cascade activated in the bone marrow
microenvironment of multiple myeloma (MM) cells and contributes to their uncontrolled …

被引用次数：6 相关文章所有 7 个版本

SN‐38, an active metabolite of irinotecan, inhibits transcription of nuclear factor erythroid 2‐related factor 2 and enhances drug sensitivity of colorectal cancer cells

J Wang, J Xu, S Yang, L He, W Xu, Y Liu… - Molecular …, 2024 - Wiley Online Library

Nuclear factor erythroid 2‐related factor 2 (Nrf2) significantly contributes to drug resistance
of cancer cells, and Nrf2 inhibitors have been vigorously pursued. Repurposing of existing …

被引用次数：1 相关文章所有 3 个版本

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[HTML][HTML] Brusatol alleviates pancreatic carcinogenesis via targeting NLRP3 in transgenic Krastm4Tyj Trp53tm1Brn Tg (Pdx1-cre/Esr1*)# Dam mice

J Zhang, YL Wu, HX Xu, YB Zhang, PY Ren… - Biomedicine & …, 2024 - Elsevier

Abstract Background Pancreatic cancer (PanCa), ranked as the 4th leading cause of cancer-
related death worldwide, exhibits an dismal 5-year survival rate of less than 5%. Chronic …

[PDF] mdpi.com