RNA editing describes targeted sequence alterations in RNAs so that the transcript
sequences differ from their DNA template. Since the original discovery of RNA editing in …

Kleinman and Majewski, Pickrell et al., and Lin et al. suggest that mapping and sequencing
errors and genetic variants led to false discovery of RNA-DNA sequence differences in our …

We have conducted a survey of RNA editing in human brain by comparing sequences of
clones from a human brain cDNA library to the reference human genome sequence and to …

Apolipoprotein (apo) B mRNA editing is a novel mechanism for the post-transcriptional
regulation of gene expression in mammals. It consists of a C--> U conversion of the first base …

A functional mooring sequence, known to be required for apolipoprotein B (apoB) mRNA
editing, exists in the mRNA encoding the neurofibromatosis type I (NF1) tumor suppressor …

With recent interest in the molecular mechanisms responsible for Fabry disease, the number
of known mutations in the GLA gene which encodes α‐galactosidase A has expanded …

For more than a decade, protein-replacement therapy has been employed successfully for
the treatment of Gaucher disease. Recently, a comparable therapy has become available for …

Paramecium telomeric DNA consists largely of a random distribution of TTGGGG and
TTTGGG repeats. Given the precise nature of other ciliate telomerases, it has been …

The vast majority of the ca. 100 chemically distinct modified nucleosides in RNA appear to
arise via the chemical transformation of a genetically encoded nucleoside. Two notable …

RNA editing Is II co-orpost-traftscriptionalp? wcess in wbicb select sucleoti& sequences In
RNA are alteredf~ m tbat originally encoded in tbe genome. T. &e mJ2NAs encohg …