Targeting NF-κB pathway for the therapy of diseases: mechanism and clinical study
H Yu, L Lin, Z Zhang, H Zhang, H Hu - Signal transduction and targeted …, 2020 - nature.com
NF-κB pathway consists of canonical and non-canonical pathways. The canonical NF-κB is
activated by various stimuli, transducing a quick but transient transcriptional activity, to …
activated by various stimuli, transducing a quick but transient transcriptional activity, to …
Epithelial–immune cell interplay in primary Sjögren syndrome salivary gland pathogenesis
GM Verstappen, S Pringle, H Bootsma… - Nature Reviews …, 2021 - nature.com
In primary Sjögren syndrome (pSS), the function of the salivary glands is often considerably
reduced. Multiple innate immune pathways are likely dysregulated in the salivary gland …
reduced. Multiple innate immune pathways are likely dysregulated in the salivary gland …
[HTML][HTML] Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
D Guo, Y Tong, X Jiang, Y Meng, H Jiang, L Du, Q Wu… - Cell metabolism, 2022 - cell.com
High expression of PD-L1 in tumor cells contributes to tumor immune evasion. However,
whether PD-L1 expression in tumor cells is regulated by the availability of nutrients is …
whether PD-L1 expression in tumor cells is regulated by the availability of nutrients is …
NF-κB and the transcriptional control of inflammation
JP Mitchell, RJ Carmody - International review of cell and molecular …, 2018 - Elsevier
The NF-κB transcription factor was discovered 30 years ago and has since emerged as the
master regulator of inflammation and immune homeostasis. It achieves this status by means …
master regulator of inflammation and immune homeostasis. It achieves this status by means …
Therapeutic potential of flavonoids in pain and inflammation: mechanisms of action, pre-clinical and clinical data, and pharmaceutical development
Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a
consequence of the pathological functioning of the nervous system rather than only a …
consequence of the pathological functioning of the nervous system rather than only a …
Regulation of NF-κB by TNF family cytokines
The NF-κB family of inducible transcription factors is activated in response to a variety of
stimuli. Amongst the best-characterized inducers of NF-κB are members of the TNF family of …
stimuli. Amongst the best-characterized inducers of NF-κB are members of the TNF family of …
Therapeutic targeting of NF-κB in acute lung injury: a double-edged sword
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a devastating disease
that can be caused by a variety of conditions including pneumonia, sepsis, trauma, and most …
that can be caused by a variety of conditions including pneumonia, sepsis, trauma, and most …
[HTML][HTML] Signal pathways in the treatment of Alzheimer's disease with traditional Chinese medicine
MR Ding, YJ Qu, B Hu, HM An - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Aim of the review This study aimed to reveal the classical signal pathways and important
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …
potential targets of traditional Chinese medicine (TCM) for treating Alzheimer's disease (AD) …
Curcumin—from molecule to biological function
T Esatbeyoglu, P Huebbe, IMA Ernst… - Angewandte Chemie …, 2012 - Wiley Online Library
Turmeric is traditionally used as a spice and coloring in foods. It is an important ingredient in
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …
curry and gives curry powder its characteristic yellow color. As a consequence of its intense …
[HTML][HTML] Anti-inflammatory effects of Rhodiola rosea L.: A review
W Pu, M Zhang, R Bai, L Sun, W Li, Y Yu… - Biomedicine & …, 2020 - Elsevier
Rhodiola rosea L., a worldwide botanical adaptogen, has been confirmed to possess
protective effects of inflammatory injury for many diseases, including cardiovascular …
protective effects of inflammatory injury for many diseases, including cardiovascular …