Biomedical applications of untethered mobile milli/microrobots

M Sitti, H Ceylan, W Hu, J Giltinan… - Proceedings of the …, 2015 - ieeexplore.ieee.org
Untethered robots miniaturized to the length scale of millimeter and below attract growing
attention for the prospect of transforming many aspects of health care and bioengineering …

Orchestrating liver development

M Gordillo, T Evans, V Gouon-Evans - Development, 2015 - journals.biologists.com
The liver is a central regulator of metabolism, and liver failure thus constitutes a major health
burden. Understanding how this complex organ develops during embryogenesis will yield …

[PDF][PDF] Biphasic activation of WNT signaling facilitates the derivation of midbrain dopamine neurons from hESCs for translational use

TW Kim, J Piao, SY Koo, S Kriks, SY Chung, D Betel… - Cell stem cell, 2021 - cell.com
Human pluripotent stem cells show considerable promise for applications in regenerative
medicine, including the development of cell replacement paradigms for the treatment of …

Synthetic hydrogels for human intestinal organoid generation and colonic wound repair

R Cruz-Acuña, M Quirós, AE Farkas, PH Dedhia… - Nature cell …, 2017 - nature.com
In vitro differentiation of human intestinal organoids (HIOs) from pluripotent stem cells is an
unparalleled system for creating complex, multicellular three-dimensional structures capable …

Rebuilding the damaged heart: mesenchymal stem cells, cell-based therapy, and engineered heart tissue

S Golpanian, A Wolf, KE Hatzistergos… - Physiological …, 2016 - journals.physiology.org
Mesenchymal stem cells (MSCs) are broadly distributed cells that retain postnatal capacity
for self-renewal and multilineage differentiation. MSCs evade immune detection, secrete an …

Cardiac cell–integrated microneedle patch for treating myocardial infarction

J Tang, J Wang, K Huang, Y Ye, T Su, L Qiao… - Science …, 2018 - science.org
We engineered a microneedle patch integrated with cardiac stromal cells (MN-CSCs) for
therapeutic heart regeneration after acute myocardial infarction (MI). To perform cell-based …

[图书][B] Molecular biology of the cell

B Alberts - 2017 - books.google.com
As the amount of information in biology expands dramatically, it becomes increasingly
important for textbooks to distill the vast amount of scientific knowledge into concise …

[HTML][HTML] Raman spectroscopy: an evolving technique for live cell studies

R Smith, KL Wright, L Ashton - Analyst, 2016 - pubs.rsc.org
One of the most exciting developments in Raman spectroscopy in the last decade has been
its application to cells and tissues for diagnostic and pharmaceutical applications, and in …

[HTML][HTML] Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome

J Tang, D Shen, TG Caranasos, Z Wang… - Nature …, 2017 - nature.com
Stem cell therapy represents a promising strategy in regenerative medicine. However, cells
need to be carefully preserved and processed before usage. In addition, cell transplantation …

Immaturity of human stem-cell-derived cardiomyocytes in culture: fatal flaw or soluble problem?

CC Veerman, G Kosmidis, CL Mummery… - Stem cells and …, 2015 - liebertpub.com
Cardiomyocytes from human pluripotent stem cells (hPSC-CMs) are increasingly used to
model cardiac disease, test drug efficacy and for safety pharmacology. Nevertheless, a …