Vitamin D is a pro-hormone characterized by an intricate metabolism and regulation. It is
well known for its role in calcium and phosphate metabolism, and in bone health. However …

The global prevalence of vitamin D deficiency appears to be increasing, and the impact of
this on human health is important because of the association of vitamin D insufficiency with …

Polymorphisms in genes encoding proteins involved in vitamin D metabolism and transport
are recognised to influence vitamin D status. Syntheses of genetic association studies …

Background Vitamin D deficiency has been associated with a multitude of disorders
including diabetes, defective insulin secretion as well as rickets and poor bone health …

Vitamin D deficiency and insufficiency as well as low serum calcium levels can trigger
negative health outcomes in women of childbearing age. Therefore, we aimed to estimate …

BACKGROUND: Vitamin D and its nuclear receptor (VDR) are linked to asthma in a genetic
and immunologic basis. Polymorphisms in the VDR gene may alter the actions of vitamin D …

The amount of variation in 25 (OH) D explained by genetic determinants is small compared
with environmental exposures. Information on genetic variants affecting 25 (OH) D can be …

Silencing of regulatory genes through hypermethylation of CpG islands is an important
mechanism in tumorigenesis. In colon cancer, RXRα, an important dimerization partner with …

Background The association between vitamin D receptor (VDR) polymorphisms and asthma
risk has been inconsistently investigated, but published studies demonstrated conflicting …

Multiple sclerosis (MS) is a neurodegenerative autoimmune disease resulting from a
complex interaction of genetic and environmental factors. Hypovitaminosis D seems to …