Drug metabolism: current concepts

C Ionescu, MR Caira - 2005 - Springer
9.4 Concluding Remarks In this chapter, the authors attempted to show how considerations
of pharmacokinetics and metabolism guide the process of developing drugs with improved …

Dietary zinc deficiency induced-changes in the activity of enzymes and the levels of free radicals, lipids and protein electrophoretic behavior in growing rats

MI Yousef, HA El Hendy, FM El-Demerdash… - Toxicology, 2002 - Elsevier
Zinc (Zn) is an essential nutrient that is required in humans and animals for many
physiological functions, including immune and antioxidant function, growth and …

Effects of riboflavin deficiency and riboflavin administration on carcinogen-DNA binding

J Pangrekar, K Krishnaswamy… - Food and chemical …, 1993 - Elsevier
A study was conducted to assess the effects of riboflavin deficiency and riboflavin
supplementation on carcinogen-DNA binding. After 12 wk on a riboflavin-sufficient or a …

Effects of benzo[a]pyrene on tissue activities of metabolizing enzymes and antioxidant system in normal and protein‐malnourished rats

OA Badary, HM AbdEl‐Gawad, RA Taha… - … of Biochemical and …, 2003 - Wiley Online Library
The effects of benzo [a] pyrene (B [a] P) on some drug‐metabolizing and antioxidant systems
in liver, lung, and stomach were investigated in normal and protein malnutrition (PM) rats …

Antioxidants as a potential therapy for reduction of oxidative stress in autistic children

N Sharaf, G Moubarz, H Awadalla… - Egyptian Journal of …, 2022 - journals.ekb.eg
Background: Recently, several studies showed oxidative stress in autism spectrum disorder
(ASD) patients. Another study found oxidative stress state and mal detoxification of …

Oxidative role of aflatoxin B1 on the liver of wheat milling workers

A Saad-Hussein, MS Abdalla, WG Shousha… - … Macedonian Journal of …, 2014 - oamjms.eu
Aim: The study aimed to estimate oxidative role of aflatoxin B1 (AFB1) on the liver in wheat
milling workers. Materials and Methods: Case-control study was conducted to compare …

Effect of administration of aroclor 1254 on the activities of hepatic drug metabolizing enzymes in zinc deficiency

V Jagadeesan - Journal of Toxicology and Environmental Health …, 1991 - Taylor & Francis
In order to understand the mechanisms of carcinogenesis in zinc deficiency, a study was
conducted in experimental animals to investigate the effect of administration of an inducer …

Arodor-Induced Changes in the Activities of Drug Metabolizing Enzymes in Zinc Deficiency and Its Relevance to Nutritional Carcinogenesis

V JAGADEESAN - PCBs: Recent Advances in Environmental …, 2015 - books.google.com
Zinc deficiency has been implicated in many abnormalities in humans, including increased
risk of cancer. In order to understand the underlying mechanisms, a comprehensive study …

[PDF][PDF] Oxidative Role of Aflatoxin B1 on the Liver of Wheat Milling Workers. OA Maced J Med Sci. 2014 Mar 15; 2 (1): 141-146

A Saad-Hussein, A MSh, S WGh, G Moubarz… - 2014 - academia.edu
Oxidative Role of Aflatoxin B1 on the Liver of Wheat Milling Workers Page 1 This article has
been published in whole in Maced J Med Sci. 2014 Mar 15; 7(1):141-146 …