Why do we not have more drugs approved for MDS? A critical viewpoint on novel drug development in MDS
SM Frumm, S Shimony, RM Stone, DJ DeAngelo… - Blood Reviews, 2023 - Elsevier
Approval of new agents to treat higher risk (HR) myelodysplastic syndrome (MDS) has
stalled since the approval of DNA methyltransferase inhibitors (DNMTi). In addition, the …
stalled since the approval of DNA methyltransferase inhibitors (DNMTi). In addition, the …
Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis
NJ Gurule, KC Malcolm, C Harris, JR Knapp… - Leukemia, 2023 - nature.com
Myelodysplastic neoplasm (MDS) is a hematopoietic stem cell disorder that may evolve into
acute myeloid leukemia. Fatal infection is among the most common cause of death in MDS …
acute myeloid leukemia. Fatal infection is among the most common cause of death in MDS …
Treatment of Anemia in Lower-Risk Myelodysplastic Syndrome
MR Battaglia, J Cannova, R Madero-Marroquin… - … Treatment Options in …, 2024 - Springer
Current Treatment Options in Oncology not a clear standard of care. For those without
previous luspatercept exposure it can be considered particularly if there is an SF3B1 …
previous luspatercept exposure it can be considered particularly if there is an SF3B1 …
Infectious Complications in Patients with Myelodysplastic Syndromes: A Report from the Düsseldorf MDS Registry
A Kasprzak, J Andresen, K Nachtkamp, A Kündgen… - Cancers, 2024 - mdpi.com
Simple Summary In patients with hematologic malignancies, especially those undergoing
intensive treatments like chemotherapy, infections pose a significant and life-threatening …
intensive treatments like chemotherapy, infections pose a significant and life-threatening …
[HTML][HTML] Patterns of lower risk myelodysplastic syndrome progression: factors predicting progression to high-risk myelodysplastic syndrome and acute myeloid …
The patterns of low-risk myelodysplastic syndrome (MDS) progression and the clinical and
molecular features of those patterns have not been well described. We divided our low-risk …
molecular features of those patterns have not been well described. We divided our low-risk …
Common cardiovascular biomarkers can independently predict outcome of patients with Myelodysplastic syndromes
I Mitroulis, V Papadopoulos, E Lamprianidou… - Blood Cancer …, 2023 - nature.com
Dear Editor, Myelodysplastic syndromes (MDS) comprise a heterogeneous group of clonal
myeloid disorders characterized by ineffective hematopoiesis and varying degrees of …
myeloid disorders characterized by ineffective hematopoiesis and varying degrees of …
Cardiac effects of deferasirox in transfusion‐dependent patients with myelodysplastic syndromes: TELESTO study
M Sarocchi, J Li, X Li, D Wu… - British Journal of …, 2024 - Wiley Online Library
Iron overload from repeated transfusions has a negative impact on cardiac function, and iron
chelation therapy may help prevent cardiac dysfunction in transfusion‐dependent patients …
chelation therapy may help prevent cardiac dysfunction in transfusion‐dependent patients …
[图书][B] Improving prognostication for patients with myelodysplastic syndromes
M Creignou - 2023 - openarchive.ki.se
Background and aims: MDS constitute a heterogenous group of myeloid malignancies
mainly characterized by dysfunctional hematopoiesis. Although cytopenia, dysplastic …
mainly characterized by dysfunctional hematopoiesis. Although cytopenia, dysplastic …
[PDF][PDF] Καρδιαγγειακοί βιοδείκτες στα μυελοδυσπλαστικά σύνδρομα
Ε Νάκου - repo.lib.duth.gr
Καρδιαγγειακοί βιοδείκτες στα Μυελοδυσπλαστικά σύνδρομα Page 1 1 ΔΗΜΟΚΡΙΤΕΙΟ
ΠΑΝΕΠΙΣΤΗΜΙΟ ΘΡΑΚΗΣ ΣΧΟΛΗ ΕΠΙΣΤΗΜΩΝ ΥΓΕΙΑΣ ΤΜΗΜΑ ΜΟΡΙΑΚΗΣ ΒΙΟΛΟΓΙΑΣ …
ΠΑΝΕΠΙΣΤΗΜΙΟ ΘΡΑΚΗΣ ΣΧΟΛΗ ΕΠΙΣΤΗΜΩΝ ΥΓΕΙΑΣ ΤΜΗΜΑ ΜΟΡΙΑΚΗΣ ΒΙΟΛΟΓΙΑΣ …
Impaired Ltb4-Induced Neutrophil Chemotactic Directionality in Myelodysplastic Neoplasms Patients
X Xie, Y Liu, L Yang, JL Ma, H Li, W Zhang… - Available at SSRN … - papers.ssrn.com
Background Myelodysplastic neoplasms (MDS) present a heightened risk of infections,
contributing significantly to morbidity and mortality. While neutrophil dysfunction is …
contributing significantly to morbidity and mortality. While neutrophil dysfunction is …