Human pathogens utilize host extracellular matrix proteins laminin and collagen for adhesion and invasion of the host
B Singh, C Fleury, F Jalalvand… - FEMS microbiology …, 2012 - academic.oup.com
Laminin (Ln) and collagen are multifunctional glycoproteins that play an important role in
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …
cellular morphogenesis, cell signalling, tissue repair and cell migration. These proteins are …
[HTML][HTML] Syphilis: using modern approaches to understand an old disease
EL Ho, SA Lukehart - The Journal of clinical investigation, 2011 - Am Soc Clin Investig
Syphilis is a fascinating and perplexing infection, with protean clinical manifestations and
both diagnostic and management ambiguities. Treponema pallidum subsp. pallidum, the …
both diagnostic and management ambiguities. Treponema pallidum subsp. pallidum, the …
[HTML][HTML] The global roadmap for advancing development of vaccines against sexually transmitted infections: update and next steps
SL Gottlieb, CD Deal, B Giersing, H Rees, G Bolan… - Vaccine, 2016 - Elsevier
Abstract In 2014, the World Health Organization, the US National Institutes of Health, and
global technical partners published a comprehensive roadmap for development of new …
global technical partners published a comprehensive roadmap for development of new …
[HTML][HTML] Protein palmitoylation and its role in bacterial and viral infections
J Sobocińska, P Roszczenko-Jasińska… - Frontiers in …, 2018 - frontiersin.org
S-palmitoylation is a reversible, enzymatic posttranslational modification of proteins in which
palmitoyl chain is attached to a cysteine residue via a thioester linkage. S-palmitoylation …
palmitoyl chain is attached to a cysteine residue via a thioester linkage. S-palmitoylation …
[HTML][HTML] Application of nanotechnology in wood-based products industry: A review
Wood-based industry is one of the main drivers of economic growth in Malaysia. Forest
being the source of various lignocellulosic materials has many untapped potentials that …
being the source of various lignocellulosic materials has many untapped potentials that …
[HTML][HTML] A defined syphilis vaccine candidate inhibits dissemination of Treponema pallidum subspecies pallidum
KV Lithgow, R Hof, C Wetherell, D Phillips… - Nature …, 2017 - nature.com
Syphilis is a prominent disease in low-and middle-income countries, and a re-emerging
public health threat in high-income countries. Syphilis elimination will require development …
public health threat in high-income countries. Syphilis elimination will require development …
Current status of syphilis vaccine development: need, challenges, prospects
CE Cameron, SA Lukehart - Vaccine, 2014 - Elsevier
Syphilis is a multistage disease caused by the invasive spirochete Treponema pallidum
subsp. pallidum. Despite inexpensive and effective antibiotic therapy, syphilis remains a …
subsp. pallidum. Despite inexpensive and effective antibiotic therapy, syphilis remains a …
[HTML][HTML] Immunization with a tri-antigen syphilis vaccine significantly attenuates chancre development, reduces bacterial load, and inhibits dissemination of …
SA Lukehart, B Molini, A Gomez, C Godornes, R Hof… - Vaccine, 2022 - Elsevier
Syphilis continues to be a significant public health concern worldwide. The disease is
endemic in many low-and middle-income countries, and rates have risen sharply in high …
endemic in many low-and middle-income countries, and rates have risen sharply in high …
Bacterial adhesins, the pathogenic weapons to trick host defense arsenal
Adhesins are bacterial proteins with host cell adhesive properties. These proteins occur in
diverse architectures, ranging from capsules, vesicles, pili, fimbri, to enzymes. These …
diverse architectures, ranging from capsules, vesicles, pili, fimbri, to enzymes. These …
Vaccine development for syphilis
KV Lithgow, CE Cameron - Expert review of vaccines, 2017 - Taylor & Francis
Introduction: Syphilis, caused by the spirochete Treponema pallidum subspecies pallidum,
continues to be a globally prevalent disease despite remaining susceptible to penicillin …
continues to be a globally prevalent disease despite remaining susceptible to penicillin …